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[呼吸高碳酸气体混合物时的血液酸碱平衡]

[Blood acid-base equilibrium during breathing of hypercapnic gas mixtures].

作者信息

Glazkova V A, Cherniakov I N

出版信息

Kosm Biol Aviakosm Med. 1975 Mar-Apr;9(2):20-7.

PMID:1123899
Abstract

By the method of Astrup-Zigaard-Andersen the acid-base balance in the blood of men and dogs exposed to hypercapnic atmospheres with a normal, increased and decreased oxygen content was investigated in 164 experiments. Variations in the acid-base equilibrium were compared with changes of physiological functions. The relationship between the acid-base balance and the carbon dioxide concentration as well as the oxygen concentration in the breathing air was established. The toxic effects of sharp hypercapnia and hyperoxia were shown to cumulate. The positive effect of moderate hypercapnia on the tolerance to normobaric hypoxia in long-term experiments was noted.

摘要

通过阿斯特鲁普-齐加德-安德森方法,在164项实验中研究了暴露于正常、升高和降低氧含量的高碳酸血症环境中的人和狗血液中的酸碱平衡。将酸碱平衡的变化与生理功能的变化进行了比较。确定了酸碱平衡与呼吸空气中二氧化碳浓度以及氧浓度之间的关系。结果表明,重度高碳酸血症和高氧血症的毒性作用会累积。注意到在长期实验中,中度高碳酸血症对常压缺氧耐受性有积极作用。

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Kosm Biol Aviakosm Med. 1975 Mar-Apr;9(2):20-7.
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