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[使用铁肺对重度高碳酸血症患者进行机械通气时动脉血的酸碱平衡(关于2例高碳酸血症后碱中毒病例)]

[Acid-base equilibrium of the arterial blood of subjects with grave hypercapnia subjected to mechanical ventilation with the iron lung (concerning 2 cases of post-hypercapnic alkalosis)].

作者信息

Ferrara A, Numeroso R, Fumagalli G

出版信息

Minerva Med. 1976 Sep 22;67(44):2877-82.

PMID:9602
Abstract

Two cases of severe chronic respiratory insufficiency in severely acute phase with disturbances in acid base balance characterized by serious gaseous acidosis are reported. Therapy was based essentially on controlled ventilotherapy using an iron lung and considerable improvements were achieved clinically with practically total normalization of the acid base imbalance after only a few hours of treatment. In the following days, however, a picture of metabolic alkalosis established itself and this is discussed and interpreted as an expression of post-hypercapnic hypochloraemia.

摘要

报告了两例处于严重急性期的严重慢性呼吸功能不全病例,其酸碱平衡紊乱以严重的气体性酸中毒为特征。治疗主要基于使用铁肺进行控制性通气疗法,治疗仅数小时后,临床症状就有了显著改善,酸碱失衡几乎完全恢复正常。然而,在接下来的几天里,出现了代谢性碱中毒的情况,并对此进行了讨论,解释为高碳酸血症后低氯血症的表现。

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