硅油相关性视神经变性。
Silicone oil-associated optic nerve degeneration.
作者信息
Budde M, Cursiefen C, Holbach L M, Naumann G O
机构信息
Department of Ophthalmology and Eye Hospital, Friedrich-Alexander Universität Erlangen-Nürnberg, Schwabachanlage 6, D-91054 Erlangen, Germany.
出版信息
Am J Ophthalmol. 2001 Mar;131(3):392-4. doi: 10.1016/s0002-9394(00)00800-x.
PURPOSE
To report the frequency and extent of silicone oil migration into the optic nerve during silicone oil endotamponade.
METHODS
Histopathologic analysis of 74 eyes enucleated after silicone oil endotamponade.
RESULTS
In 14 of 74 enucleated eyes (24%), optically empty vacuoles regarded as silicone oil vacuoles were observed in the retrolaminar optic nerve. In three eyes, silicone oil in the optic nerve was surrounded by a granulomatous inflammatory reaction. In serial cross sections, the vacuoles extended up to the line of surgical transsection (up to 9 mm) of the optic nerve and constituted up to 40% of the total cross-sectional area.
CONCLUSIONS
After silicone oil endotamponade, silicone oil may replace a considerable amount of tissue of the retrolaminar optic nerve. A granulomatous inflammatory reaction surrounding silicone oil may add to optic nerve damage.
目的
报告硅油眼内填充期间硅油迁移至视神经的频率和范围。
方法
对74只硅油眼内填充后摘除眼球进行组织病理学分析。
结果
在74只摘除眼球中的14只（24%），在视神经管后段观察到被视为硅油空泡的光学上无内容物的空泡。在三只眼中，视神经内的硅油被肉芽肿性炎症反应包绕。在连续切片中，空泡延伸至视神经手术横断处（达9毫米），并占总横截面积的40%。
结论
硅油眼内填充后，硅油可能替代视神经管后段的大量组织。围绕硅油的肉芽肿性炎症反应可能加重视神经损伤。
Zotero 插件