El-Migdadi F, Khatib S Y, Bashir N
Department of Biochemistry, School of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Biochemistry (Mosc). 2001 Jan;66(1):96-8. doi: 10.1023/a:1002846032470.
This study was designed to investigate the effect of exercise at 350 m below sea level altitude (-350 m) on the serum levels of lactate dehydrogenase (LDH), insulin, and lactate. The study was carried out on ten trained adult males with mean age of 23.3 +/- 3.4 years following a 21-km noncompetitive run. Venous blood was withdrawn from the subjects before exercise and 5 min post exercise. For comparison purposes, a similar study was performed with the same subjects but at 620 m above sea level (+620 m). The results show a significant increase in LDH and lactate levels after exercise only at low altitude (-350 m). Serum insulin levels decreased significantly after exercise at both altitudes. These changes in serum levels of LDH, insulin, and lactate at different altitudes suggest that a type of metabolic adjustment is present that meets energy requirements during exercise.
本研究旨在调查海平面以下350米（-350米）高度的运动对血清乳酸脱氢酶（LDH）、胰岛素和乳酸水平的影响。该研究针对10名训练有素的成年男性进行，他们的平均年龄为23.3±3.4岁，进行了一次21公里的非竞争性跑步。在运动前和运动后5分钟从受试者身上采集静脉血。为了进行比较，对相同的受试者在海拔620米（+620米）的高度进行了类似的研究。结果显示，仅在低海拔（-350米）运动后，LDH和乳酸水平显著升高。在两个海拔高度运动后，血清胰岛素水平均显著下降。不同海拔高度下血清LDH、胰岛素和乳酸水平的这些变化表明，存在一种代谢调节类型，可满足运动期间的能量需求。
