Lévy E, Lévy P
LEGOS, Université Paris-Dauphine, Place du Maréchal de Lattre de Tassigny, 75775 Paris Cedex 16, France.
J Mal Vasc. 2001 Feb;26(1):39-44.
The purpose of this study was to better ascertain how French physicians manage venous ulcers of the lower limbs. We explored the various therapeutic approaches used and their respective costs. Particular attention was focused on dressing prescriptions.
A prospective medicoeconomic study was conducted. Eight hundred general practitioners and specialists throughout France were included and followed two patients each, one with a "new ulcer" (less than two weeks) and another with a "longstanding ulcer" (more than six weeks). Patients were followed to healing or for up to six months. An observation chart was completed at each visit. Data collected were characteristics of the ulcer at inclusion, assessment of the clinical course, and the nature and the volume of medical care prescribed. Corresponding costs (total cost for the society) were calculated on the basis of 1996 public prices for drugs and the French national health insurance quotations for ambulatory care. For hospital care, cost was calculated from the cost of stay for homogeneous patient groups.
Files established for 1,098 patients by 652 physicians could be assessed. Elderly female patients predominated in this population (mean age 72 years, 74% women). The length of the ulcer at inclusion was significantly correlated with its duration: 2.82 cm for new ulcers (52.6% of the cases) versus 5.03 cm for longstanding ulcers (47.3%). The mean number of consultations for all patients was 4.8 over a 29-day period. Mean cost resulting from these consultations was 5,827 FF per patient: 48% for care, 33 for drugs, 16% for hospitalizations, and 3% for work lay-off ). Cure was achieved in 77% of the cases within a mean delay of 3 months. Older ulcer was significantly associated with longer treatment (117 days for longstanding ulcers versus 80 days for new ulcers), lower cure rate (67% versus 86%) and higher cost (7 078 FF versus 4 669 FF). Dividing care methods between those using cleaning with compression or not showed that compression was prescribed in 76% of the cases at the inclusion consultation. This predominance of compression therapy did not preclude use of a variety of other therapeutic methods depending on the clinical and demographic situation of the patient. Cost varied accordingly with a mean ranging from 3 160 FF to 6 697 FF depending on the therapeutic attitude. The study also focused on the type and amount of dressings used. Dressings were prescribed for 56 patients in this series. It can be hypothesized that these patients already had dressings. Different indicators show that the absence of prescriptions for dressings concerned less severe and less costly ulcers (4 130 FF versus 5 918 FF for those with dressing prescriptions). Among the 1 042 patients for whom dressings were prescribed, 35% were for occlusive dressings, 29% for ointment dressings and also 24% for both occlusive and ointment dressings. The type was not specified in 55% of the cases. Mean cost for these different categories ranged from 4 921 to 7 019 FF.
本研究旨在更好地确定法国医生如何治疗下肢静脉溃疡。我们探讨了各种治疗方法及其各自的成本。特别关注敷料处方。
进行了一项前瞻性医学经济学研究。纳入了法国各地的800名全科医生和专科医生,每位医生跟踪两名患者,一名患有“新溃疡”(不到两周),另一名患有“长期溃疡”(超过六周)。对患者进行跟踪直至愈合或长达六个月。每次就诊时填写一份观察表。收集的数据包括纳入时溃疡的特征、临床病程评估以及所开医疗护理的性质和数量。相应的成本(社会总成本)根据1996年药品的公共价格和法国国家医疗保险门诊护理报价计算。对于住院治疗,成本根据同类患者群体的住院费用计算。
652名医生为1098名患者建立的档案可供评估。该人群中老年女性患者居多(平均年龄72岁,74%为女性)。纳入时溃疡的长度与其持续时间显著相关:新溃疡为2.82厘米(52.6%的病例),而长期溃疡为5.03厘米(47.3%)。所有患者在29天内的平均就诊次数为4.8次。这些就诊产生的平均成本为每位患者5827法郎:护理占48%,药物占33%,住院占16%,误工占3%。77%的病例在平均3个月的延迟内治愈。溃疡时间较长与治疗时间较长(长期溃疡为117天,新溃疡为80天)、治愈率较低(67%对86%)和成本较高(7078法郎对4669法郎)显著相关。将护理方法分为使用或不使用加压清洁的方法,结果显示在纳入咨询时76%的病例开具了加压治疗。加压疗法的这种主导地位并不排除根据患者的临床和人口统计学情况使用各种其他治疗方法。成本相应有所不同,根据治疗态度,平均成本从3160法郎到6697法郎不等。该研究还关注了所用敷料的类型和数量。本系列中有56名患者开具了敷料处方。可以推测这些患者已经有敷料。不同指标表明,未开具敷料处方的溃疡病情较轻且成本较低(开具敷料处方的患者为4130法郎,未开具的为5918法郎)。在开具敷料处方的1042名患者中,35%使用封闭性敷料,29%使用软膏敷料,24%同时使用封闭性和软膏敷料。55%的病例未注明类型。这些不同类别的平均成本从4921法郎到7019法郎不等。