Kase H., Aoki Y., Sugaya S., Takakuwa K., Tanaka K.
Department of Obstetrics and Gynecology, Niigata University School of Medicine, Niigata, Japan.
Int J Gynecol Cancer. 2000 Nov;10(6):507-509. doi: 10.1046/j.1525-1438.2000.00078.x.
Palmar fasciitis and polyarthritis (PFPA) is an uncommon syndrome characterized by progressive and extensive rheumatic disease. We present the first example of PFPA in association with squamous cell carcinoma of the uterine cervix and peritoneal carcinoma. A 54-year-old woman developed pain in both shoulders and flexion deformities of all fingers in both hands due to an increasing swelling of both palms. She underwent surgery and histologic examination of the removed uterus revealed squamous cell carcinoma, nonkeratinizing type with a small portion of undifferentiated carcinoma. Chemotherapy resulted in an excellent response, during which the arthritic symptoms improved gradually. PFPA can occur in a wide range of cancers and warrants extensive investigation for a malignant tumor.
掌腱膜挛缩症和多关节炎（PFPA）是一种罕见的综合征，其特征为进行性广泛性风湿性疾病。我们报告了首例与子宫颈鳞状细胞癌和腹膜癌相关的PFPA。一名54岁女性因双手掌肿胀加剧出现双肩疼痛和双手所有手指屈曲畸形。她接受了手术，切除子宫的组织学检查显示为鳞状细胞癌，非角化型，伴有一小部分未分化癌。化疗取得了极佳的效果，在此期间关节炎症状逐渐改善。PFPA可发生于多种癌症，因此对于恶性肿瘤需要进行广泛的调查。
