Kajikawa Hiroyuki, Sobajima Takuya, Koiwai Chinatsu, Ichigo Satoshi, Takagi Hiroshi, Imai Atsushi
Department of Obstetrics and Gynecology, Matsunami General Hospital, Kasamatsu, Gifu 501-6062, Japan.
Department of General Internal Medicine, Matsunami General Hospital, Kasamatsu, Gifu 501-6062, Japan.
Mol Clin Oncol. 2018 Feb;8(2):292-295. doi: 10.3892/mco.2017.1509. Epub 2017 Nov 24.
Palmar fasciitis and polyarthritis (PFPA) is an uncommon disorder clinically characterized by rapidly developing bilateral arthritis of the hands and fasciitis of the palms. This cancer-associated syndrome, primarily linked to ovarian cancer, has also been associated with multiple different malignancies. PFPA symptoms usually precede the detection of ovarian cancer. In all patients from case series and single case reports described, ovarian cancer is already present at an advanced stage. Therefore, the authors aimed to present a case and systematically review available evidence on the association between PFPA and ovarian cancer, as gynecological oncologists. Awareness and recognition of PFPA may allow for earlier diagnosis and treatment of an occult ovarian cancer. The commitment of the attending gynecologists to become familiar with and identify rare diseases may lead to the detection at an early and curative stage and potentially life-saving therapeutic interventions.
掌腱膜挛缩症和多关节炎（PFPA）是一种罕见的疾病，临床特征为双手迅速发展的双侧关节炎和手掌筋膜炎。这种与癌症相关的综合征主要与卵巢癌有关，也与多种不同的恶性肿瘤相关。PFPA症状通常先于卵巢癌的检测出现。在所有病例系列和单病例报告中描述的患者中，卵巢癌在诊断时已处于晚期。因此，作为妇科肿瘤学家，作者旨在介绍一例病例并系统回顾关于PFPA与卵巢癌之间关联的现有证据。认识和识别PFPA可能有助于早期诊断和治疗隐匿性卵巢癌。主治妇科医生致力于熟悉和识别罕见疾病，可能会在早期治愈阶段检测到疾病，并进行可能挽救生命的治疗干预。
