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《脑病与肝脏疾病(作者译)》

[Encephalopathy and liver diseases (author's transl)].

作者信息

Kunze K

出版信息

MMW Munch Med Wochenschr. 1979 May 18;121(20):697-700.

PMID:112411
Abstract

As the central organ of metabolism the liver is of the highest importance for the nervous system and for the brain in particular, which only becomes apparent under pathological conditions. It is of importance to neurologists that for them the differential diagnosis of subclinical or chronic intermittent decompensating types of hepatic encephalopathy is predominant. We are actually concerned here with encephalomyeloneuropathies which become manifest by failure on the part of the spinal marrow and the peripheral nervous system. Among the various hepatocerebral diseases the rare Wilson's disease and sporadic Wilsonismus should be mentioned from the differential diagnostic point of view, and especially the differential diagnosis of the porphyrias should be given attention, since they may first appear spontaneously and suddenly under metabolic stress, e. g. anesthesia.

摘要

作为新陈代谢的中心器官,肝脏对神经系统,尤其是对大脑极为重要,这一点只有在病理情况下才会显现出来。对神经科医生来说重要的是,对他们而言,亚临床或慢性间歇性失代偿型肝性脑病的鉴别诊断占主导地位。实际上,我们这里关注的是脊髓和周围神经系统功能衰竭而表现出的脑脊髓神经病。从鉴别诊断的角度来看,在各种肝脑疾病中,应提及罕见的威尔逊氏病和散发性威尔逊氏病,尤其应注意卟啉病的鉴别诊断,因为它们可能在代谢应激(如麻醉)下首次自发突然出现。

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