Kosasa T S, Pion R J, Hale R W, Goldstein D P, Taymor M L, Levesque L A, Kobara T Y
Obstet Gynecol. 1975 May;45(5):566-8.
Fifty-one women with missed periods ranging from 5 to 14 days who suspected a pregnancy underwent an aspiration curettage with a flexible soft-tipped cannula attached to a Karman-type syringe. Sera from these women were measured for human chorionic gonadotropin (hCG) by a rapid 2-hour solid phase radioimmunoassay using an antibody with a specificity for the beta subunit of hCG. The sensitivity and specificity of this assay insured detection of bCG with 100% accuracy at the time of the missed period. Of the 51 women, 33 (64.7%) were found to have hCG in their serum, and 29 (56.8%) had histologic evidence diagnostic of pregnancy.
51名月经推迟5至14天且怀疑怀孕的女性接受了刮宫术，使用的是连接卡尔曼式注射器的软头可弯曲套管。通过一种快速2小时固相放射免疫测定法，使用对人绒毛膜促性腺激素（hCG）β亚基具有特异性的抗体，对这些女性的血清进行hCG检测。该检测方法的灵敏度和特异性确保在月经推迟时能100%准确检测到bCG。在这51名女性中，33名（64.7%）血清中检测到hCG，29名（56.8%）有组织学证据诊断为怀孕。
