Beggs W H, Andrews F A
Res Commun Chem Pathol Pharmacol. 1975 Jan;10(1):185-8.
A divalent cation-dependent antagonism of dihydrostreptomycin action on Mycobacterium smegmatis was demonstrated. However, the nutritionally nonessential cations Sr++ and Ba++ inhibited drug action as effectively as the essential ions Mg++ and Ca++, indicating a high degree of nonspecificity.
已证明二价阳离子对二氢链霉素作用于耻垢分枝杆菌具有依赖性拮抗作用。然而，营养非必需阳离子Sr++和Ba++对药物作用的抑制效果与必需离子Mg++和Ca++一样有效，这表明存在高度的非特异性。
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