二氢链霉素对耻垢分枝杆菌作用中，二价阳离子拮抗作用的非特异性
Nonspecificity in the divalent cation antagonism of dihydrostreptomycin action on Mycobacterium smegmatis.
作者信息
Beggs W H, Andrews F A
出版信息
Res Commun Chem Pathol Pharmacol. 1975 Jan;10(1):185-8.
PMID:1124316
Abstract
A divalent cation-dependent antagonism of dihydrostreptomycin action on Mycobacterium smegmatis was demonstrated. However, the nutritionally nonessential cations Sr++ and Ba++ inhibited drug action as effectively as the essential ions Mg++ and Ca++, indicating a high degree of nonspecificity.
摘要
已证明二价阳离子对二氢链霉素作用于耻垢分枝杆菌具有依赖性拮抗作用。然而，营养非必需阳离子Sr++和Ba++对药物作用的抑制效果与必需离子Mg++和Ca++一样有效，这表明存在高度的非特异性。
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