Vassella F, Pfenninger J
Schweiz Med Wochenschr. 1975 Mar 1;105(9):263-6.
Some specific pediatric aspects of therapy with antibiotics and other chemotherapeutic agents (dosage based on age, body weight and body surface area) are discussed. In early infancy problems such as the "immaturity" of enzyme systems and excretion mechanisms must be considered. Tetracycline staining is discussed as an example of age-dependent vulnerability of organs. A selection of antibiotics suitable for use in ambulatory pediatrics is proposed.
讨论了抗生素和其他化疗药物治疗的一些特定儿科方面(基于年龄、体重和体表面积的剂量)。在婴儿早期,必须考虑酶系统和排泄机制“不成熟”等问题。以四环素染色为例讨论了器官的年龄依赖性易损性。提出了一系列适用于门诊儿科的抗生素。