Marshak T L
Sov J Dev Biol. 1975 Mar;5(2):166-71.
The formation of binuclear tetraploid cells in the pigmented epithelium of the retina and the rat liver was investigated by the method of autoradiography using H3-thymidine. It was shown that binuclear cells are formed in these tissues as a result of incomplete mitosis. Only mononuclear diploid cells participate in the formation of these cells in the livers of 24-day-old animals, while in the pigmented epithelium of the retina of four-day-old animals, in addition binuclear tetraploid cells also participate. The duration of the phases of the mitotic cycle of cells of the pigmented epithelium of the rat retina and liver was determined.
采用H3-胸腺嘧啶核苷放射自显影法，对大鼠视网膜色素上皮和肝脏中双核四倍体细胞的形成进行了研究。结果表明，这些组织中的双核细胞是不完全有丝分裂的结果。在24日龄动物的肝脏中，只有单核二倍体细胞参与这些细胞的形成，而在4日龄动物视网膜色素上皮中，除单核二倍体细胞外，双核四倍体细胞也参与其中。还测定了大鼠视网膜色素上皮和肝脏细胞有丝分裂周期各阶段的持续时间。
