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西奥多·埃米尔·科赫尔,现代外科先驱

[Theodor Emil Kocher, modern surgery pioneer].

作者信息

Chigot J P

机构信息

Service de chirurgie générale, digestive et endocrinienne, hôpital de la Pitié-Salpêtrière, 83, boulevard de l'Hôpital, 75651 Paris, France.

出版信息

Ann Chir. 2000 Nov;125(9):884-92.

Abstract

Theodore Kocher was awarded the Nobel Prize in 1909 for his work on the physiology, pathology and surgery of the thyroid gland. He was the first Swiss citizen and the first surgeon to ever receive such a distinction. He was a pioneer and a world leader in the surgical revolution of the end of the nineteenth century. After graduation in 1865, he traveled in Germany, England, France and Austria to observe the work of Langenbeck, Paget, Wells, Nelaton, Billroth.... In 1866, he returned to Bern and was appointed assistant in the surgical clinic of Lücke. In 1872 he applied for the succession of Lücke. After a lively debate, he was appointed by the Board of Regents against the recommendation of the faculty who wished to nominate a German surgeon, König. It proved to be a good choice, as, over a period of 45 years, Kocher developed a considerable activity in various fields of surgery leading to world-wide acclaim and renown. Kocher's most significant contribution to medicine concerned the thyroid gland. He considerably improved thyroid surgery. His anatomical knowledge, precise operating technic and respect of the aseptic principles defined by Lister, whom he had met in Glasgow, contributed to a reduction of mortality from 13% to 0.18%. He described postoperative hypothyroidism, which he called cachexia strumipriva and concluded that total thyroidectomy was not indicated in benign diseases. When he died, more than 7,000 thyroidectomies had been performed in his clinic. Kocher was also interested in orthopedics, abdominal and genitourinary surgery, surgical oncology, neurosurgery (Cushing conducted experimental research with him). He developed or modified many surgical instruments. He conducted a large number of experimental studies and published 249 articles and books.

摘要

西奥多·科赫尔于1909年因在甲状腺的生理学、病理学及外科手术方面的工作而被授予诺贝尔奖。他是首位获得这一殊荣的瑞士公民及外科医生。他是19世纪末外科革命的先驱及世界领军人物。1865年毕业后,他游历德国、英国、法国和奥地利,观摩了朗根贝克、佩吉特、韦尔斯、内拉通、比尔罗特等人的工作。1866年,他回到伯尔尼,被任命为吕克外科诊所的助理。1872年,他申请接替吕克的职位。经过一番激烈辩论,董事会不顾希望提名德国外科医生柯尼希的教员们的建议,任命了他。事实证明这是个明智的选择,因为在45年的时间里,科赫尔在外科的各个领域都开展了大量活动,赢得了全球的赞誉和声誉。科赫尔对医学最重大的贡献与甲状腺有关。他极大地改进了甲状腺手术。他的解剖学知识、精确的手术技巧以及对他在格拉斯哥结识的李斯特所定义的无菌原则的遵循,使得死亡率从13%降至0.18%。他描述了术后甲状腺功能减退症,称之为甲状腺切除术后恶病质,并得出结论,良性疾病无需进行全甲状腺切除术。他去世时,他的诊所已进行了7000多例甲状腺切除术。科赫尔还对骨科、腹部及泌尿生殖外科、外科肿瘤学、神经外科(库欣曾与他进行实验研究)感兴趣。他研发或改进了许多外科器械。他进行了大量实验研究,发表了249篇文章和书籍。

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