Robert C M, Stern W E, Brown W J, Greenfield M A, Bentson J R
Surg Neurol. 1975 Mar;3(3):153-60.
A 10-year-old girl, with congenital heart disease, harboring a brain stem abscess, was recently treated at the UCLA Hospital. Needle aspirations of the abscess was performed through a posterior occipital craniectomy, and thorium dioxide (Thorotrast) was placed within the abscess cavity as a marker. Postoperatively, the patient improved temporarily but died 18 days later. Autopsy examination included radioactive analysis of brain and liver tissue. Radioautographs were superimposed on H&E preparations of the abscess wall to localize the extent of activity of the thorium dioxide. The unusual occurrence of this abscess in a young patient, clinically diagnosed and treated by operation, provided a rare opportunity to assess the problem of the surgical accessibility of brain stem abscess as well as to reevaluate a role for thorium dioxide as a marker for intracranial purulent collections.
一名患有先天性心脏病且伴有脑干脓肿的10岁女孩，近期在加州大学洛杉矶分校医疗中心接受了治疗。通过枕后颅骨切除术对脓肿进行了针吸，并将二氧化钍（钍造影剂）置于脓肿腔内作为标记物。术后，患者暂时有所好转，但18天后死亡。尸检包括对脑和肝组织进行放射性分析。将放射自显影片叠加在脓肿壁的苏木精-伊红染色切片上，以确定二氧化钍的活性范围。该脓肿在一名年轻患者中罕见出现，经临床诊断并接受手术治疗，为评估脑干脓肿的手术可及性问题以及重新评估二氧化钍作为颅内脓性病灶标记物的作用提供了难得的机会。
