Is there any relation between ischemic cerebrovascular disease and extracranial internal carotid stenosis?

OBJECTIVES

To confirm the existence of plaque or stenosis in the extracranial carotid arteries of patients with transient ischemia attack (TIA) or stroke, and to analyze the prevalence of extracranial carotid atherosclerotic stenosis, as well as the relation between the hemispheric symptoms and the degree of stenosis.

METHODS

From January 1995 to March 1996, 188 patients underwent routine carotid artery duplex scan at Zhongshan Hospital, Shanghai. Of the 188 patients, 134 had TIA or stroke in the carotid territory during the previous 12 months, 54 were with peripheral arterial occlusive disease (PAOD). All patients were divided into three groups, that is, stroke/TIA group (Group 1, n = 128), PAOD group (Group 2, n = 36), and stroke/TIA + PAOD group (Group 3, n = 24). The classification of degree of stenosis in our study was as same as that applied by North American Symptomatic Carotid Endarterectomy Trial (NASCET) and European Carotid Surgery Trial (ECST).

RESULTS

A total of 376 internal carotid arteries were examined by duplex scanning in this study. The prevalence of severe stenosis in the three groups was 12.5%, 8.3% and 37.5% separately. The severity of stenosis had a close relation with patients' symptoms (P < 0.01).

CONCLUSIONS

Patients with stroke or TIA have atherosclerotic plaques in the carotid arteries. The prevalence of extracranial carotid stenosis is comparable to that reported in the literature. PAOD may be helpful to identify patients at high risk for severe carotid stenosis. Carotid duplex scanning should be performed as a routine examination for patients with stroke, TIA, and PAOD.