锂诱导的肾性尿崩症。

Lithium-induced nephrogenic diabetes insipidus.

作者信息

Eustatia-Rutten C F, Tamsma J T, Meinders A E

机构信息

Department of General Internal Medicine, LUMC, C1-R, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.

出版信息

Neth J Med. 2001 Mar;58(3):137-42. doi: 10.1016/s0300-2977(00)00104-2.

DOI:10.1016/s0300-2977(00)00104-2

PMID:11246113

Abstract

Two patients with severe lithium-induced nephrogenic diabetes insipidus are described. Although it is known lithium can cause diabetes insipidus, one should be especially alert in psychiatric patients, as the main defence mechanisms thirst and drinking behaviour may not function adequately in these patients. The major form of therapy in both patients consisted of drinking, a thiazide diuretic, as well as a protein and sodium restricted diet.

摘要

本文描述了两名患有严重锂诱导性肾性尿崩症的患者。虽然已知锂可导致尿崩症，但在精神科患者中应格外警惕，因为这些患者的主要防御机制——口渴和饮水行为可能无法正常发挥作用。两名患者的主要治疗方式包括饮水、服用噻嗪类利尿剂以及限制蛋白质和钠的饮食。