精神分裂症中的情感症状学：迟发性运动障碍的一个危险因素？

Affective symptomatology in schizophrenia: a risk factor for tardive dyskinesia?

作者信息

Schulze T G, Müller D J, Krauss H, Marwinski K, Maroldt A O, Novo Y Fernández A, Fimmers R, Held T, Maier W, Nöthen M M, Rietschel M

机构信息

Department of Psychiatry, University of Bonn, Sigmund-Freud-Str. 25, Germany.

出版信息

Eur Psychiatry. 2001 Feb;16(1):71-4. doi: 10.1016/s0924-9338(00)00539-3.

DOI:10.1016/s0924-9338(00)00539-3

PMID:11246296

Abstract

Affective symptomatology has repeatedly been suggested to confer susceptibility to tardive dyskinesia (TD). In our sample of 174 schizophrenic patients a history of depressive symptoms was not associated with the occurrence of TD, whereas manic symptomatology was significantly associated with the absence of TD. Thus, our data suggest that affective symptomatology cannot unambiguously be considered to predispose to TD.

摘要

情感症状学一再被认为会使人易患迟发性运动障碍（TD）。在我们174名精神分裂症患者的样本中，抑郁症状史与TD的发生无关，而躁狂症状学与无TD显著相关。因此，我们的数据表明，情感症状学不能被明确认为是TD的易患因素。