Zdziechowska H, Gepner-Woźniewska M, Krzyzanowska-Woźniakowska J, Zywicka-Lopaciuk H, Sobczyńska Z, Michalski R
Acta Haematol Pol. 1975 Jan-Mar;6(1):27-35.
The authors analysed 202 cases of chronic lymphatic leukaemia comparing the course of this disease in patients above and below 60 years of age. The observation included patients with various forms of this disease--with morphological and clinical findings compatible with mild disease and cases with severe course with complications. It was observed that in severe form of lymphatic leukaemia the course of the disease is similar in both groups of patients and the shorter survival of patients in the older group is frequently due to coexistence of other diseases impairing the general condition and changes connected age. On the other hand, a mild, oligosymptomatic course of the disease was observed more frequently in older patients who did not require intense treatment in hospitals.
作者分析了202例慢性淋巴细胞白血病病例,比较了60岁及以上和60岁以下患者的病程。观察对象包括患有该疾病各种形式的患者——其形态学和临床特征与轻度疾病相符的患者,以及病程严重并伴有并发症的患者。据观察,在严重形式的淋巴细胞白血病中,两组患者的病程相似,老年组患者生存期较短往往是由于并存其他损害总体健康状况的疾病以及与年龄相关的变化。另一方面,在无需住院进行强化治疗的老年患者中,更常观察到疾病呈轻度、症状较少的病程。