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1970年赫尔辛基65岁及以下人群中缺血性心脏病死亡情况,特别提及心脏的病理解剖学发现。?211.

Deaths from ischemic heart disease in persons aged 65 or younger in Helsinki in 1970 with special reference to patho-anatomic findings in hearts.?211.

作者信息

Rissanen V, Romo M, Sarna S, Siltanen P

出版信息

Acta Med Scand. 1975 Jan-Feb;197(1-2):51-60. doi: 10.1111/j.0954-6820.1975.tb04877.x.

DOI:10.1111/j.0954-6820.1975.tb04877.x
PMID:1124661
Abstract

Deaths from ischemic heart disease(IHD) occurring during a period of one year in Helsinki in persons aged 65 years or younger have been investigated by the Ischaemic Heart Disease Register. Altogether 526 fatalities were registered. Autopsy data were collected in 432 cases, the autopsy rate being 82 percent. The results are presented separately for persons autopsied in the pathologic departments, representing mostly delayed deaths in hospitals, and for medico-legally autopsied persons representing sudden deaths outside hospitals. The diagnosis of IHD death was either based on the positive patho-anatomic or clinical evidence of an acute heart attack or supported by a history of clinical IHD in 92 percent of all registered fatal cases. In the remaining fatalities the possibility of other causes of death had been more or less definitely excluced. All persons with an acute attack of IHD and all autopsied cases showed a division into four socio-economic groups very similar to that of the population of Helsinki. Men belonging to the lowest social group were over-represented among medico-legally autopsied cases. A history of a previous heart disease, visits to a doctor and the use of digitalis were less common in persons autopsied medico-legally than in those autopsied in the pathologic departments. In the former an acute infarction was most often located in the posterior wall and in the latter in the anterior wall of the left ventricle. The prevalence of an occlusion was highest in the right coronary artery in the former and in the left anterior descending coronary artery in the latter; In medico-legally autopsied cases in which a recent myocardial infarction was observed the interventricular septum was involved in 81 percent, but in cases with an old infarction the septum was involved in only 52 percent. No difference in the size of the hearts, the frequency of an old infarction or the prevalence of coronary occlusions was found between persons autopsied in the pathologic and forensic departments. Although a previous angina was about equally common in both sexes, old infarctions were more common in men. The increase in heart weight had occurred proportionally to the same extent in both sexes.

摘要

赫尔辛基缺血性心脏病登记处对65岁及以下人群在一年时间内死于缺血性心脏病(IHD)的情况进行了调查。共登记了526例死亡病例。收集了432例尸检数据,尸检率为82%。结果分别呈现给在病理科进行尸检的人员(大多代表医院内的延迟死亡)以及经法医尸检的人员(代表医院外的猝死)。在所有登记的死亡病例中,92%的IHD死亡诊断要么基于急性心脏病发作的阳性病理解剖或临床证据,要么有临床IHD病史支持。在其余死亡病例中,其他死因的可能性已或多或少被明确排除。所有急性发作IHD的患者和所有尸检病例都被分为四个社会经济群体,这与赫尔辛基的人口分布非常相似。在经法医尸检的病例中,属于最低社会群体的男性比例过高。与在病理科进行尸检的人员相比,经法医尸检的人员中既往心脏病史、看医生的次数和使用洋地黄的情况较少。在前者中,急性梗死最常位于后壁,而在后者中最常位于左心室前壁。在前者中,右冠状动脉闭塞的发生率最高,在后者中,左前降支冠状动脉闭塞的发生率最高;在经法医尸检且观察到近期心肌梗死的病例中,81%的病例室间隔受累,但在有陈旧性梗死的病例中,室间隔受累的仅占52%。在病理科和法医科进行尸检的人员之间,心脏大小、陈旧性梗死的频率或冠状动脉闭塞的发生率没有差异。尽管既往心绞痛在男女中同样常见,但陈旧性梗死在男性中更常见。男女心脏重量的增加程度相同。

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引用本文的文献

1
Prehospital sudden death from ischaemic heart disease. A postmortem study.缺血性心脏病导致的院外猝死。一项尸检研究。
Br Heart J. 1978 Sep;40(9):1025-33. doi: 10.1136/hrt.40.9.1025.