Rew D A
Royal South Hearts Cancer Centre, Southampton University Hospitals, UK.
Eur J Surg Oncol. 2001 Feb;27(1):105-8. doi: 10.1053/ejso.2000.1039.
The genome of the fruit fly has recently been sequenced, prior to the release of the human genome sequence within the next few years. The fly has some 13 600 genes, compared with the estimated 80 000 genes in the human genome. Some 70% of genes appear to be broadly conserved across eukaryotic species, and some remarkable homologies have been found between 177 genes in the fly and the 289 human genes so far associated with diseases in man. The fruit fly genome is likely to prove an elegant model and a rich source of experimentation for the aetiology and regulation of human cancers.
果蝇的基因组最近已被测序，这是在未来几年人类基因组序列公布之前。果蝇大约有13600个基因，而人类基因组估计有80000个基因。约70%的基因似乎在真核生物物种中广泛保守，并且在果蝇的177个基因与目前已发现的289个与人类疾病相关的人类基因之间发现了一些显著的同源性。果蝇基因组可能会被证明是研究人类癌症病因学和调控的一个完美模型和丰富的实验来源。
