Khanam H, Lipper M H, Wolff C L, Lopes M B
University of Virginia Health Sciences Center, Department of Pathology, Box 800-214, Charlottesville, VA 22908-0214, USA.
Surg Neurol. 2001 Jan;55(1):63-7; discussion 67. doi: 10.1016/s0090-3019(00)00268-8.
Primary hemangiomas of the bone are uncommon tumors, accounting for less than 1.0% of all bone neoplasms. These tumors are mostly found in vertebral bodies. Hemangiomas are rarely seen in the calvarium, where their frequency is 0.2% of all bone neoplasms. Because of their infrequent appearance in the skull, vague symptoms, and absence of prototypical radiological findings, these tumors can be missed in many cases or may be misinterpreted as more ominous lesions like multiple myeloma or osteosarcoma.
We report two cases of calvarial hemangiomas: one with a single mass on the right sphenoid wing, and another with two similar lesions on the right occipital and left parietal bones. The diagnoses could be established only by histopathologic analysis.
Histopathologic confirmation of the tumor is the definitive method for diagnosis of intraosseous hemangiomas. Radiological findings are not always characteristic for calvarial hemangiomas. Due to possible complications and the possibility of effective treatment, this lesion should always be considered in the differential diagnosis of skull lesions.
骨原发性血管瘤是罕见肿瘤，占所有骨肿瘤的比例不到1.0%。这些肿瘤大多见于椎体。血管瘤在颅骨中很少见，其在所有骨肿瘤中的发生率为0.2%。由于它们在颅骨中出现频率低、症状不明确且缺乏典型的影像学表现，这些肿瘤在许多病例中可能被漏诊，或可能被误诊为更凶险的病变，如多发性骨髓瘤或骨肉瘤。
我们报告两例颅骨血管瘤病例：一例右侧蝶骨翼有单个肿块，另一例右侧枕骨和左侧顶骨有两个类似病变。仅通过组织病理学分析才能确诊。
肿瘤的组织病理学确诊是诊断骨内血管瘤的决定性方法。颅骨血管瘤的影像学表现并不总是具有特征性。由于可能出现并发症且有有效治疗的可能性，在颅骨病变的鉴别诊断中应始终考虑这种病变。
