Segal M S, Ishikawa S
Ann Allergy. 1975 Apr;34(4):205-9.
Notable acute improvement in pulmonary function in the majority of 32 patients with known bronchial asthma followed two inhalations of Isoproterenol. No deleterious clinical or cardiovascular effects of EKG changes (after one-half hour) were observed. A slight drop in blood pressure was noted in previously hypertensive patients. Isoproterenol's short duration of effects is ideal and one or two inhalations spaced four hours apart may be safely recommended for the relief of the acute asthma paroxysm.
32例已知支气管哮喘患者中有多数在吸入两次异丙肾上腺素后肺功能显著急性改善。未观察到(半小时后)心电图改变产生有害的临床或心血管效应。既往高血压患者出现血压略有下降。异丙肾上腺素作用持续时间短很理想,可安全推荐每隔4小时吸入一或两次以缓解急性哮喘发作。