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Co-administration of tacrolimus and mycophenolate mofetil does not increase mycophenolic acid (MPA) exposure, but co-administration of cyclosporine inhibits the enterohepatic recirculation of MPA, thereby decreasing its exposure.

作者信息

Van Gelder T, Klupp J, Barten M J., Christians U, Morris R E.

机构信息

1University Hospital Rotterdam, Rotterdam, The Netherlands; 2Stanford University, Stanford, CA; 3UCSF, San Francisco, CA, USA

出版信息

J Heart Lung Transplant. 2001 Feb;20(2):160-161. doi: 10.1016/s1053-2498(00)00289-8.

DOI:10.1016/s1053-2498(00)00289-8
PMID:11250239
Abstract
摘要

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Influence of cyclosporine and everolimus on the main mycophenolate mofetil pharmacokinetic parameters: Cross-sectional study.环孢素和依维莫司对霉酚酸酯主要药代动力学参数的影响：横断面研究。
Medicine (Baltimore). 2017 Mar;96(13):e6469. doi: 10.1097/MD.0000000000006469.
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