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Mutations in the TGF-beta type 1 receptor, ALK1, in combined primary pulmonary hypertension and hereditary haemorrhagic telangiectasia, implies pathway specificity.

作者信息

Trembath R C.

机构信息

University of Leicester, Leicester, United Kingdom

出版信息

J Heart Lung Transplant. 2001 Feb;20(2):175. doi: 10.1016/s1053-2498(00)00352-1.

DOI:10.1016/s1053-2498(00)00352-1
PMID:11250282
Abstract
摘要

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Mutations in the TGF-beta type 1 receptor, ALK1, in combined primary pulmonary hypertension and hereditary haemorrhagic telangiectasia, implies pathway specificity.转化生长因子β1型受体（ALK1）的突变在合并原发性肺动脉高压和遗传性出血性毛细血管扩张症中，提示了通路特异性。
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