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[胃内异尖线虫病——来自德国的一例病例报告]

[Anisakiasis of the stomach--a case report from Germany].

作者信息

Plath F, Holle A, Zendeh D, Möller F W, Barten M, Reisinger E C, Liebe S

机构信息

Klinik und Poliklinik für Innere Medizin, Abteilung für Gastroenterologie, Medizinische Fakultät der Universität Rostock.

出版信息

Z Gastroenterol. 2001 Feb;39(2):177-80. doi: 10.1055/s-2001-11150.

Abstract

Anisakiasis or "herring worm disease" is one of the most important parasitic diseases of the gastrointestinal tract in Japan. In 1988 Lorenz and Warzok published 8 cases of intestinal anisakiasis in Eastern Germany. In 1988 Spehn et al. reported a case of gastric anisakiasis in an AIDS patient. Here, we describe a case of gastric anisakiasis in Germany with an impressive serious clinical course. The symptoms--acute abdominal cramps, severe chest pain, diarrhoea, sub-febrile temperatures and leucocytosis--followed 4 h after consumption of raw herring, which was homemade pickled in vinegar. The conventional and the endoscopic ultrasonography showed a thickened gastric wall made of mainly thickened submucosa. The larvae of Anisakis in the gastric mucosa were found and extracted endoscopically. Acute and severe abdominal pain after eating raw fish is an indication for early gastroscopy. The endoscopical extraction of possible larvae is the only effective therapy, as anthelmintics against nematodes (mebendazole, albendazole, thiabendazole) are ineffective.

摘要

异尖线虫病或“鲱鱼蠕虫病”是日本最重要的胃肠道寄生虫病之一。1988年,洛伦兹和瓦尔佐克发表了东德8例肠道异尖线虫病病例。1988年,施彭等人报告了1例艾滋病患者的胃异尖线虫病病例。在此,我们描述1例德国胃异尖线虫病病例,其临床病程严重且令人印象深刻。症状——急性腹部绞痛、严重胸痛、腹泻、低热和白细胞增多——在食用自制醋腌生鲱鱼4小时后出现。传统检查和内镜超声检查显示胃壁增厚,主要是黏膜下层增厚。在内镜下发现并取出了胃黏膜中的异尖线虫幼虫。食用生鱼后出现急性剧烈腹痛是早期进行胃镜检查的指征。由于抗线虫驱虫药(甲苯达唑、阿苯达唑、噻苯达唑)无效,内镜下取出可能存在的幼虫是唯一有效的治疗方法。

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