Di Cataldo A, Dollo C, Astuto M, La Spina M, Ippolito S, Papotto M, Giuffrida S
Department of Pediatric Hematology/Oncology, University of Catania, Catania, Italy.
Pediatr Hematol Oncol. 2001 Mar;18(2):117-21. doi: 10.1080/088800101300002946.
The authors report two pediatric cases of transient mutism that occurred after surgical removal of a medulloblastoma and a pilocytic astrocytoma of the vermis and discuss the pathophysiology of this syndrome. Transient mutism has been described for the first time quite recently, even in cases where these tumors were also surgically removed before. Perhaps improvement in imaging and in surgical techniques made neurosurgeons more daring and some interventions that were judged impossible are routinely performed today. If this is the case, postoperative transient cerebellar mutism might be considered the price that must be paid in order to cure more patients with cerebellar tumors.
作者报告了两例小儿短暂性缄默症病例，分别发生在髓母细胞瘤以及小脑蚓部毛细胞型星形细胞瘤手术切除后，并讨论了该综合征的病理生理学。短暂性缄默症直到最近才首次被描述，即使在之前也曾对这些肿瘤进行手术切除的病例中也是如此。或许成像技术和手术技术的进步让神经外科医生更加大胆，一些过去被认为不可能的干预如今已常规进行。如果是这样的话，术后短暂性小脑缄默症可能被视为治愈更多小脑肿瘤患者必须付出的代价。
