Mális V
Klinika oftalmológie MFN a JLF UK, Martin.
Cesk Slov Oftalmol. 2001 Jan;57(1):22-6.
The aim of this prospective study has been to evaluate effectivity of laser peripheral iridoplasty (ALPI) as a first choice therapy for intraocular pressure (IOP) reduction in acute primary angle-closure glaucoma (PACG). The study included 12 patients with the first attack of acute glaucoma in whom IOP in spite of continuing medical therapy for 12 hours persisted at the level of 5.32 kPa (40.0 mmHg) and higher. We used Argon laser manufactured by HGM E-005. Laser parameters were: spot size 300-500 um, time 0.2-0.5 s, intensity 300-500 mW. Laser burns were placed to the whole circumference of the iridocorneal angle numbering 50-60 with the use of Goldmann contact lens. Applanation tonometry was used to measure IOP shortly before the laser therapy and 1 and 2 hours after ALPI. The mean IOP prior to treatment was 6.00 +/- 1.46 kPa (51.7 +/- 11.04 mmHg). The mean IOP 1 hour after ALPI was 2.77 +/- 0.44 kPa (20.83 +/- 3.31 mmHg) and after 2 hours 2.39 +/- 0.26 kPa (18.0 +/- 2.0 mmHg) which represents 45.8% reduction in IOP. Two hours after treatment all patients had transparent corneas. The results of this study confirm that ALPI effectively reduces IOP and enhances transparency of the cornea in acute PACG for the definitive treatment by laser iridotomy.
这项前瞻性研究的目的是评估激光周边虹膜成形术（ALPI）作为急性原发性闭角型青光眼（PACG）降低眼压（IOP）的首选治疗方法的有效性。该研究纳入了12例首次发作急性青光眼的患者，尽管持续药物治疗12小时，但眼压仍维持在5.32 kPa（40.0 mmHg）及以上。我们使用了HGM E - 005制造的氩激光。激光参数为：光斑大小300 - 500 um，时间0.2 - 0.5 s，强度300 - 500 mW。使用戈德曼接触镜在虹膜角膜角的整个圆周上进行50 - 60次激光烧灼。在激光治疗前以及ALPI治疗后1小时和2小时使用压平眼压计测量眼压。治疗前平均眼压为6.00 +/- 1.46 kPa（51.7 +/- 11.04 mmHg）。ALPI治疗后1小时平均眼压为2.77 +/- 0.44 kPa（20.83 +/- 3.31 mmHg），2小时后为2.39 +/- 0.26 kPa（18.0 +/- 2.0 mmHg），眼压降低了45.8%。治疗2小时后所有患者角膜均透明。本研究结果证实，ALPI能有效降低急性PACG的眼压，并提高角膜透明度，以便通过激光虹膜切开术进行确定性治疗。
