Verna E
Divisione di Cardiologia Ospedale del Circolo Via Borri, 57 21100 Varese.
Ital Heart J Suppl. 2001 Feb;2(2):116-7.
The Editorial Board of the Italian Heart Journal Supplement has planned to publish a series of four consecutive papers focusing on new highlights from the cardiac catheterization laboratory, developments of new devices, coronary imaging and physiological measurement. The first paper on cineless digital angiography and new fluoroscopy systems presented in this issue of the Journal has been prepared by Danzi et al. (Brescia). The paper follows the publication of the Vergara's work (Rovereto-TN) on a similar topic presented last year in a Symposium of the Gruppo Italiano di Studi Emodinamici (GISE) at the XXXI ANMCO meeting. The recent development of cineless digital angiography and the increasing interest in new digital fluoroscopic low energy systems represent a significant change in the management of cardiac images and have significant implications in the organization of a new catheterization laboratory. The second paper will focus on the clinical applications of intravascular ultrasound imaging and will be prepared by Di Mario (Milan). Intravascular ultrasound imaging has significantly contributed to the understanding of vascular adaptation to coronary artery disease and mechanisms of percutaneous coronary interventions. This new diagnostic approach is particularly useful in assessing the early stages of disease, evaluating occult atherosclerosis and guiding the strategy of coronary interventions. Unfortunately, the application of intravascular ultrasound imaging in clinical practice remains limited. The third paper prepared by Verna (Varese) will discuss the new techniques for physiological evaluation of coronary artery disease now available in the catheterization laboratory. The use of pressure and Doppler flow-wire in the assessment of functional significance of individual coronary artery stenoses and in the evaluation of the vasodilatory capacity of coronary microcirculation may provide new insights for the clinical decision at the catheterization table. In addition, the application of myocardial contrast echocardiography with new sonicated agents for intracoronary use may represent a novel approach to the direct evaluation of regional myocardial perfusion and microvascular integrity. Intracoronary stenting has become a widely used and accepted technique in percutaneous coronary interventions. The fourth article of this series, prepared by Silva (Milan), will discuss the advantages and limitations of stenting in different clinical settings based on the results of large clinical trials. In spite of the growing number of procedures safely performed in many countries, long-term results of intracoronary stenting may be sometimes disappointing in selected patients. In-stent restenosis still represents a clinical problem limiting long-term outcome. In addition, the increasing use of new antiplatelet agents in combination with most stenting procedures rise some concern about overall cost of interventions. The objective of this editorial program is to give a view of the changing scenario of the catheterization laboratory with the new methods and devices presently available. There may be significant implications and controversial issues of interest also for all clinical cardiologists.
《意大利心脏杂志增刊》编辑委员会计划连续发表四篇论文,重点关注心导管实验室的新亮点、新设备的研发、冠状动脉成像及生理测量。本期杂志发表的第一篇关于无胶片数字血管造影和新型透视系统的论文由丹齐等人(布雷西亚)撰写。该论文继去年在第三十一届意大利心脏病学会(ANMCO)会议上举行的意大利血流动力学研究小组(GISE)研讨会上韦尔加拉(罗韦雷托-特伦托)发表的关于类似主题的作品之后。无胶片数字血管造影的最新进展以及对新型数字低能透视系统日益增长的兴趣代表了心脏影像管理方面的重大变化,并且对新的心导管实验室的组织具有重要意义。第二篇论文将聚焦血管内超声成像的临床应用,将由迪马里奥(米兰)撰写。血管内超声成像极大地促进了对血管适应冠状动脉疾病及经皮冠状动脉介入治疗机制的理解。这种新的诊断方法在评估疾病早期阶段、评估隐匿性动脉粥样硬化以及指导冠状动脉介入治疗策略方面特别有用。遗憾的是,血管内超声成像在临床实践中的应用仍然有限。由韦尔纳(瓦雷泽)撰写的第三篇论文将讨论目前在心导管实验室可用于冠状动脉疾病生理评估的新技术。在评估单个冠状动脉狭窄的功能意义以及评估冠状动脉微循环的血管舒张能力时使用压力和多普勒血流导丝可能为心导管检查台上的临床决策提供新的见解。此外,将新型超声造影剂用于冠状动脉内的心肌对比超声心动图的应用可能代表了一种直接评估局部心肌灌注和微血管完整性的新方法。冠状动脉内支架置入术已成为经皮冠状动脉介入治疗中广泛使用且被认可的技术。本系列的第四篇文章由席尔瓦(米兰)撰写,将根据大型临床试验结果讨论在不同临床情况下支架置入术的优缺点。尽管许多国家安全实施的手术数量不断增加,但冠状动脉内支架置入术在某些特定患者中的长期结果有时可能令人失望。支架内再狭窄仍然是一个限制长期预后的临床问题。此外,在大多数支架置入手术中越来越多地联合使用新型抗血小板药物引发了对干预总体成本的一些担忧。本编辑计划的目的是展示心导管实验室随着目前可用的新方法和新设备而不断变化的情况。这对于所有临床心脏病学家来说也可能存在重大影响和有争议的问题。