Niaura R, Britt D M, Shadel W G, Goldstein M, Abrams D, Brown R
Brown University Center for Behavioral and Preventive Medicine, Miriam Hospital, 164 Summit Avenue, Providence, Rhode Island 02906, USA.
Psychol Addict Behav. 2001 Mar;15(1):13-7. doi: 10.1037/0893-164x.15.1.13.
Symptoms of depression have been associated with increased smoking prevalence and failure to quit smoking in several cross-sectional and population-based studies. Few studies, however, have prospectively examined the ability of current symptoms of depression to predict failure to quit smoking in treatment-motivated smokers. Pretreatment depressed mood was assessed by 3 different methods in 3 separate samples, 2 of which comprised smokers receiving combined pharmacological and behavioral treatments and a 3rd in which smokers received self-help materials only. In all studies, time in days from quit day until the 1st cigarette was ascertained to document survival. Survival analyses showed that in all 3 studies survival time was significantly and negatively related to measures of even very low levels of pretreatment depressed mood. Results were replicated across 3 independent samples and were robust and uniformly clear, indicating that low levels of depressive symptoms assessed at baseline predict time to 1st cigarette smoked after attempted quitting.
在一些横断面研究和基于人群的研究中，抑郁症状与吸烟率上升及戒烟失败有关。然而，很少有研究前瞻性地考察当前抑郁症状对有戒烟意愿的吸烟者戒烟失败的预测能力。在3个独立样本中，通过3种不同方法评估了治疗前的抑郁情绪，其中2个样本中的吸烟者接受了药物和行为联合治疗，第3个样本中的吸烟者仅收到了自助材料。在所有研究中，确定从戒烟日到吸第一支烟的天数以记录持续时间。生存分析表明，在所有3项研究中，即使是非常低水平的治疗前抑郁情绪指标，其持续时间与生存时间均呈显著负相关。结果在3个独立样本中得到重复，且稳健一致，表明基线时评估的低水平抑郁症状可预测戒烟尝试后吸第一支烟的时间。
