与青霉胺治疗类风湿关节炎相关的重症肌无力。
Myasthenia gravis associated with penicillamine treatment for rheumatoid arthritis.
作者信息
Bucknall R C, Dixon A St J, Glick E N, Woodland J, Zutshi D W
出版信息
Br Med J. 1975 Mar 15;1(5958):600-2. doi: 10.1136/bmj.1.5958.600.
Abstract
Four patients with rheumatoid arthritis (R.A.) developed myasthenia gravis after taking penicillamine. In one patient withdrawal of the drug was followed by spontaneous remission of the myasthenia, and in two the dose of anticholinesterase was subsequently reduced. In the fourth patient continuing penicillamine treatment was associated with increasingly severe myasthenic features, but on withdrawal of the drug these resolved. As myasthenia gravis rarely complicates R.A. its onset in these patients shortly after the start of penicillamine treatment suggested that penicillamine may have precipitated this condition.
摘要
四名类风湿性关节炎（R.A.）患者在服用青霉胺后患上了重症肌无力。其中一名患者停药后重症肌无力自发缓解，另外两名患者随后抗胆碱酯酶药物剂量减少。第四名患者继续使用青霉胺治疗时，重症肌无力症状日益严重，但停药后症状消失。由于重症肌无力很少并发类风湿性关节炎，这些患者在开始服用青霉胺后不久就出现这种疾病，提示青霉胺可能诱发了该病。
相似文献
1
Myasthenia gravis associated with penicillamine treatment for rheumatoid arthritis.与青霉胺治疗类风湿关节炎相关的重症肌无力。
Br Med J. 1975 Mar 15;1(5958):600-2. doi: 10.1136/bmj.1.5958.600.
2
[Penicillamine-induced myasthenia in chronic rheumatoid arthritis (author's transl)].青霉胺诱发慢性类风湿关节炎中的肌无力（作者译）
Dtsch Med Wochenschr. 1976 Jul 30;101(31):1153-8. doi: 10.1055/s-0028-1104232.
3
Penicillamine-induced myasthenia gravis in a patient with rheumatoid arthritis. A case report.青霉胺诱发类风湿关节炎患者重症肌无力。病例报告。
S Afr Med J. 1981 Sep 19;60(12):478.
4
Plasma exchange therapy for severe penicillamine-induced myasthenia gravis.
J Rheumatol. 1981 Mar-Apr;8(2):303-7.
5
[D-penicillamine-induced myasthenia gravis].[青霉胺诱发的重症肌无力]
Schweiz Med Wochenschr. 1994 May 21;124(20):852-6.
6
[Myasthenic syndrome during penicillamine treatment (author's transl)].青霉胺治疗期间的肌无力综合征（作者译）
Klin Wochenschr. 1978 Feb 1;56(3):139-44. doi: 10.1007/BF01478569.
7
D-penicillamine and the ocular myasthenic syndrome.D-青霉胺与眼肌型重症肌无力综合征
Ann Ophthalmol. 1981 Oct;13(10):1171-2.
8
Penicillamine-induced ocular myasthenia gravis in rheumatoid arthritis.青霉胺诱发类风湿关节炎患者的眼重症肌无力
J Clin Neuroophthalmol. 1990 Sep;10(3):201-5.
9
D-penicillamine induced myasthenia gravis. Its relevance for the anaesthetist.
Br J Anaesth. 1986 Oct;58(10):1191-3. doi: 10.1093/bja/58.10.1191.
10
D-penicillamine-induced myasthenia gravis: diagnosis obscured by coexisting chronic obstructive pulmonary disease.青霉胺诱发的重症肌无力：并存慢性阻塞性肺疾病掩盖诊断
Am J Med Sci. 1995 Apr;309(4):191-3. doi: 10.1097/00000441-199504000-00001.
引用本文的文献
1
New onset of myasthenia gravis after intravesical Bacillus Calmette-Guerin: A case report and literature review.膀胱内灌注卡介苗后新发重症肌无力：一例报告及文献复习
Medicine (Baltimore). 2017 Nov;96(46):e8757. doi: 10.1097/MD.0000000000008757.
2
Potassium channel complex autoimmunity induced by inhaled brain tissue aerosol.吸入脑组织气溶胶诱导的钾通道复合物自身免疫。
Ann Neurol. 2012 Mar;71(3):417-26. doi: 10.1002/ana.22674.
3
Myasthenic crisis.重症肌无力危象
Neurocrit Care. 2005;3(3):189-94. doi: 10.1385/NCC:3:3:189.
4
Clinical implementation of anti-acetylcholine receptor antibodies.抗乙酰胆碱受体抗体的临床应用
J Neurol Neurosurg Psychiatry. 1993 May;56(5):496-504. doi: 10.1136/jnnp.56.5.496.
5
Anti-acetylcholine receptor antibodies.抗乙酰胆碱受体抗体
J Neurol Neurosurg Psychiatry. 1980 Jul;43(7):590-600. doi: 10.1136/jnnp.43.7.590.
6
Induction of auto-immune syndromes by penicillamine therapy in rheumatoid arthritis and other diseases.青霉胺治疗类风湿关节炎及其他疾病时引发自身免疫综合征
Springer Semin Immunopathol. 1981;4(2):193-207. doi: 10.1007/BF01857095.
7
Antirheumatic drugs: clinical pharmacology and therapeutic use.抗风湿药物：临床药理学与治疗应用。
Drugs. 1980 Dec;20(6):453-84. doi: 10.2165/00003495-198020060-00002.
8
Historical perspectives on penicillamine.青霉胺的历史视角
J R Coll Physicians Lond. 1980 Apr;14(2):130-6.
9
Inhibition of human helper T cell function in vitro by D-penicillamine and CuSO4.青霉胺和硫酸铜在体外对人辅助性T细胞功能的抑制作用。
J Clin Invest. 1980 May;65(5):1069-76. doi: 10.1172/JCI109759.
10
Pathogenesis and treatment of myasthenia gravis.重症肌无力的发病机制与治疗
Br Med J (Clin Res Ed). 1981 Oct 17;283(6298):1008-12. doi: 10.1136/bmj.283.6298.1008.
本文引用的文献
1
SJOEGREN'S SYNDROME. A CLINICAL, PATHOLOGICAL, AND SEROLOGICAL STUDY OF SIXTY-TWO CASES.干燥综合征。62例的临床、病理及血清学研究。
Medicine (Baltimore). 1965 May;44:187-231.
2
DIAGNOSTIC criteria for rheumatoid arthritis: 1958 revision by a committee of the American Rheumatism Association.类风湿关节炎的诊断标准：美国风湿病协会委员会1958年修订版。
Ann Rheum Dis. 1959 Mar;18(1):49-51; French transl 51-2; Spanish transl 52-3.
3
Rheumatic diseases in patients with myasthenia gravis. An epidemiological and clinical investigation.重症肌无力患者的风湿性疾病。一项流行病学和临床调查。
Acta Neurol Scand. 1968;44(2):219-27. doi: 10.1111/j.1600-0404.1968.tb05568.x.
4
Curare sensitivity and myastheniform symptoms in patients with rheumatoid arthritis.
Acta Rheumatol Scand. 1969;15(1):54-61. doi: 10.3109/rhe1.1969.15.issue-1-4.08.
5
Myasthenia gravis as an autoimmune disease: clinical aspects.重症肌无力作为一种自身免疫性疾病：临床方面。
Ann N Y Acad Sci. 1966 Jan 26;135(1):506-16. doi: 10.1111/j.1749-6632.1966.tb45499.x.
6
Antibiotic-induced neuromuscular blockade.抗生素诱导的神经肌肉阻滞。
Ann N Y Acad Sci. 1971 Sep 15;183:358-68. doi: 10.1111/j.1749-6632.1971.tb30765.x.
Zotero 插件