Muñoz Alameda L E, Barcina Sánchez M
Servicio de Anestesiología y Reanimación, Fundación Jiménez Díaz, Avda. Reyes Católicos, 2, 28040 Madrid.
Rev Esp Anestesiol Reanim. 2001 Feb;48(2):71-80.
Nicardipine is a calcium antagonist belonging to the dihydropyridine group of molecules. An intravenous formulation has recently become available, offering certain advantages over other drugs in this group, given that it lacks their negative inotropic effects and its vasodilator effect favors coronary and cerebral artery beds. Nicardipine lowers arterial pressure in proportion to plasma levels by means of a reduction in systemic vascular resistance produced by relaxation of arteriolar smooth muscle. It has been suggested that nicardipine has a protective effect on the myocardium.
尼卡地平是一种属于二氢吡啶类分子的钙拮抗剂。一种静脉制剂最近已上市，与该组中的其他药物相比具有某些优势，因为它没有它们的负性肌力作用，且其血管舒张作用有利于冠状动脉和脑动脉床。尼卡地平通过使小动脉平滑肌松弛产生的全身血管阻力降低，使动脉压与血浆水平成比例降低。有人认为尼卡地平对心肌有保护作用。
