Deshpande P V, Jones K V
University Hospital of Wales, University of Wales College of Medicine, Heath Park, Cardiff CF14 4XN, UK.
Arch Dis Child. 2001 Apr;84(4):324-7. doi: 10.1136/adc.84.4.324.
To assess the outcome of imaging investigations carried out in children with urinary tract infection (UTI), to compare the investigations with national guidelines, and to assess the impact on management.
Retrospective review of inpatients and outpatients, aged 0-12 years, referred to the University Hospital of Wales Healthcare Trust between February 1997 and January 1998 with UTI. All children without bacterial evidence of UTI and children previously investigated for antenatal urological anomalies, major congenital anomalies, or UTI were excluded.
A total of 164 children (51 boys, 113 girls) were included. Thirteen of 56 infants (23%) and 82/108 older children (76%) were diagnosed at home over one year. The prevalence of dilatation on ultrasound was 8%, renal scarring on dimercaptosuccinic acid (DMSA) scan was 11%, and vesicoureteric reflux (VUR) was 34% when investigations were carried out following guidelines published by the Royal College of Physicians. In children aged 1-6 years, the prevalence of scarring was 1/54 (2%) in those treated at home and 6/18 (33%) in inpatients.
The low yield of positive results and lack of evidence of impact on management indicate that DMSA scanning, with all the implications of isotope exposure, intravenous injection, staff time, psychological trauma, and expense, could be omitted in children over 1 year with first simple UTI not sufficiently ill to be admitted to hospital. The low rate of detection of UTI in primary care in infants may represent under diagnosis.
评估对患有泌尿道感染(UTI)的儿童进行影像学检查的结果,将这些检查与国家指南进行比较,并评估其对治疗管理的影响。
对1997年2月至1998年1月期间转诊至威尔士大学医院医疗信托基金的0至12岁住院和门诊UTI患儿进行回顾性研究。排除所有无UTI细菌学证据的儿童以及先前因产前泌尿系统异常、重大先天性异常或UTI接受过检查的儿童。
共纳入164名儿童(51名男孩,113名女孩)。56名婴儿中有13名(23%)以及108名大龄儿童中有82名(76%)在一年多的时间里在家中被诊断出患病。按照皇家内科医师学院发布的指南进行检查时,超声检查显示扩张的患病率为8%,二巯基丁二酸(DMSA)扫描显示肾瘢痕形成的患病率为11%,膀胱输尿管反流(VUR)的患病率为34%。在1至6岁的儿童中,在家接受治疗的患儿瘢痕形成的患病率为1/54(2%),住院患儿为6/18(33%)。
阳性结果的低检出率以及缺乏对治疗管理有影响的证据表明,对于首次发生单纯性UTI且病情不严重无需住院的1岁以上儿童,可以省略DMSA扫描,因为该检查涉及同位素暴露、静脉注射、医护人员时间、心理创伤和费用等诸多问题。婴儿初级保健中UTI的低检出率可能代表诊断不足。