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本文引用的文献

1
Palatability and cost comparison of five liquid corticosteroid formulations.五种液体皮质类固醇制剂的适口性和成本比较
J Pediatr Oncol Nurs. 1999 Apr;16(2):74-7. doi: 10.1177/104345429901600205.
2
Bioavailability assessment of a liquid prednisone preparation.一种液体泼尼松制剂的生物利用度评估。
J Allergy Clin Immunol. 1982 Oct;70(4):243-7. doi: 10.1016/0091-6749(82)90060-4.
3
A clinical scoring system for the diagnosis of respiratory failure. Preliminary report on childhood status asthmaticus.一种用于诊断呼吸衰竭的临床评分系统。儿童重症哮喘状态的初步报告。
Am J Dis Child. 1972 Mar;123(3):227-8. doi: 10.1001/archpedi.1972.02110090097011.

用于急性哮喘的泼尼松龙片或口服溶液，碾碎服用？

Crushed prednisolone tablets or oral solution for acute asthma?

作者信息

Lucas-Bouwman M E, Roorda R J, Jansman F G, Brand P L

机构信息

Department of Paediatrics, Isala klinieken/Weezenlanden Hospital, PO Box 10500, 8000 GM Zwolle, Netherlands.

出版信息

Arch Dis Child. 2001 Apr;84(4):347-8. doi: 10.1136/adc.84.4.347.

DOI:10.1136/adc.84.4.347
PMID:11259239
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1718704/
Abstract

In a randomised trial, treatment with prednisolone in two formulations (oral solution or crushed tablets) was compared in 78 young children with acute asthma. Prednisolone oral solution was better tolerated than crushed tablets (less vomiting, superior taste); clinical resolution was similar.

摘要

在一项随机试验中，对78名患有急性哮喘的幼儿比较了两种剂型（口服溶液或压碎片剂）的泼尼松龙治疗效果。泼尼松龙口服溶液的耐受性优于压碎片剂（呕吐更少，味道更好）；临床缓解情况相似。