Hemminki K, Bolund L
Cell Differ. 1975 Mar;3(6):347-59. doi: 10.1016/0045-6039(75)90003-2.
Synthesis of nuclear histones and nonhistones was studied in chick oviduct during stimulation with estrogen and progesterone. In estrogen primed chicks, as compared to progesterone primed chicks, oviduct nonhistones are enriched in polypeptides of 50,000 daltons and larger. A secondary stimulation with the steroids increases the amino acid incorporation into histones and nonhistones two to six fold. Injection with estrogen induces preferential labelling of nonhistone polypeptides at 50,000 to 60,000 daltons independent of the kind of primary stimulation. A secondary injection with progesterone increases the amounts of highly labelled polypeptides with a molecular weight of over 70,000 daltons.
在雌激素和孕酮刺激下，研究了雏鸡输卵管中核心组蛋白和非组蛋白的合成。与经孕酮预处理的雏鸡相比，经雌激素预处理的雏鸡输卵管非组蛋白富含50000道尔顿及以上的多肽。用这些类固醇进行二次刺激可使氨基酸掺入组蛋白和非组蛋白的量增加2至6倍。注射雌激素可诱导50000至60000道尔顿的非组蛋白多肽优先标记，且与初次刺激的类型无关。二次注射孕酮会增加分子量超过70000道尔顿的高标记多肽的量。
