Biswal B M, Kareem A, Ahmed N M
Department of Radiotherapy and Oncology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.
Australas Radiol. 2001 Feb;45(1):71-3. doi: 10.1046/j.1440-1673.2001.00883.x.
A patient with nasopharyngeal carcinoma developed clubbing and hypertrophic osteoarthropathy 6 months before radiological detection of secondary deposits in the lung. Another patient with nasopharyngeal carcinoma developed digital clubbing and hypertrophic osteoarthropathy 6 months after the discovery of lung metastases. Development of a paraneoplastic syndrome in the form of hypertrophic osteoarthropathy and digital clubbing is very rare. This manifestation of nasopharyngeal cancers is presented, with a short review of its biology and pathogenesis.
一名鼻咽癌患者在肺部继发性沉积物经放射学检测出6个月前出现杵状指和肥大性骨关节病。另一名鼻咽癌患者在发现肺转移后6个月出现杵状指和肥大性骨关节病。以肥大性骨关节病和杵状指形式出现的副肿瘤综合征非常罕见。本文介绍了鼻咽癌的这一表现，并对其生物学和发病机制进行了简要综述。
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