McColl M D, Tait R C, Greer I A, Walker I D
Department of Haematology, Ayrshire and Arran Acute Hospitals NHS Trust, Crosshouse Hospital, Kilmarnock KA2 0BE, UK.
Br J Haematol. 2001 Mar;112(3):641-3. doi: 10.1046/j.1365-2141.2001.02633.x.
Three hundred and twenty-two consecutive women aged 16-70 years who presented with objectively confirmed symptomatic venous thromboembolism (VTE) were studied to determine precipitating factors for thrombosis. One hundred and eighty-seven presented with deep vein thrombosis (DVT), 116 with either definite or possible pulmonary embolism (PE) and 19 with both DVT and PE. Injecting drug use (IDU) via femoral vein puncture was a common risk factor for DVT, associated with 21.4% of all cases of DVT and 52.4% of cases of DVT in women under 40 years. All women with drug-related thrombosis presented with DVT. None presented with symptomatic PE. A number of clinically diagnosed DVT associated with IDU were also documented, suggesting that IDU may be the most common risk factor for DVT in our region. DVT associated with IDU presents significant management challenges.
对322名年龄在16至70岁之间、经客观证实患有症状性静脉血栓栓塞症（VTE）的连续女性进行了研究，以确定血栓形成的诱发因素。其中187人患有深静脉血栓形成（DVT），116人患有确诊或可能的肺栓塞（PE），19人同时患有DVT和PE。通过股静脉穿刺注射毒品（IDU）是DVT的常见危险因素，在所有DVT病例中占21.4%，在40岁以下女性的DVT病例中占52.4%。所有与药物相关的血栓形成的女性均表现为DVT。无人表现出症状性PE。还记录了一些临床诊断为与IDU相关的DVT，这表明IDU可能是我们地区DVT最常见的危险因素。与IDU相关的DVT带来了重大的管理挑战。
