Holme S A, Anstey A V
Department of Dermatology, University Hospital of Wales, Cardiff, UK.
Clin Exp Dermatol. 2001 Jan;26(1):40-1. doi: 10.1046/j.1365-2230.2001.00757.x.
Aquagenic pruritus is a rare but distinct entity in which intense itching develops after contact with water, in the absence of cutaneous signs or underlying disorders that could explain the symptoms. The aetiology is currently unknown, and treatment difficult, with a poor response to antihistamines. Psoralen-ultra violet A (PUVA) photochemotherapy can be effective, but frequent maintenance therapy may be required to prevent relapse of symptoms. We present a patient with typical aquagenic pruritus who responded well to PUVA, and who has remained well controlled on infrequent maintenance.
水源性瘙痒症是一种罕见但独特的病症，即在接触水后会出现强烈瘙痒，且不存在可解释这些症状的皮肤体征或潜在疾病。其病因目前尚不清楚，治疗困难，对抗组胺药反应不佳。补骨脂素 - 紫外线A（PUVA）光化学疗法可能有效，但可能需要频繁的维持治疗以防止症状复发。我们报告一位患有典型水源性瘙痒症的患者，其对PUVA反应良好，且通过不频繁的维持治疗病情得到了很好的控制。
