Weisshaar Elke, Müller Simon, Szepietowski Jacek C, Dalgard Florence, Garcovich Simone, Kupfer Jörg, Gimenez-Arnau Ana, Lambert Julien, Mettang Thomas, Misery Laurent, Savk Ekin, Tschachler Erwin, Wallengren Joanna, Ständer Sonja
Section of Occupational Dermatology, Department of Dermatology, Ruprecht-Karls-University Heidelberg, Germany.
Department of Dermatology, Universitätsspital Basel, Switzerland.
Acta Derm Venereol. 2025 Aug 22;105:adv44220. doi: 10.2340/actadv.v105.44220.
Pruritus is a frequent symptom in medicine. Population-based studies show that one in five persons in the general population has suffered from chronic pruritus (CP) at least once in their lifetime, with a 12-month incidence of 7%. CP, which can affect all age groups, is associated with numerous, often interdisciplinary medical conditions. It needs a precise diagnostic work-up to identify causes and relevant comorbidities. Management of CP comprises treatment of the underlying disease as well as topical and systemic therapies. Treating CP needs to be targeted, multimodal and performed in a step-wise procedure requiring an interdisciplinary approach. In recent years, novel on-label therapies have been approved for CP, including therapies for chronic prurigo and cholestatic pruritus. We present the updated European guideline on chronic pruritus by a team of European pruritus experts from different disciplines.
瘙痒是医学中常见的症状。基于人群的研究表明，普通人群中五分之一的人一生中至少患过一次慢性瘙痒（CP），12个月发病率为7%。CP可影响所有年龄组，与众多往往涉及多学科的医疗状况相关。它需要精确的诊断检查以确定病因和相关合并症。CP的管理包括基础疾病的治疗以及局部和全身治疗。治疗CP需要有针对性、多模式且按逐步程序进行，这需要跨学科方法。近年来，新型的有适应证的疗法已被批准用于CP，包括治疗慢性痒疹和胆汁淤积性瘙痒的疗法。我们展示了由来自不同学科的欧洲瘙痒症专家团队制定的最新版欧洲慢性瘙痒指南。
