• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

西班牙南部安达卢西亚吉普赛人群体中HLA II类等位基因分布情况。

HLA class II allele distribution in the Gypsy community of Andalusia, southern Spain.

作者信息

Ramal L M, de Pablo R, Guadix M J, Sánchez J, Garrido A, Garrido F, Jiménez-Alonso J, López-Nevot M A

机构信息

Servicio de Análisis Clínicos, Hospital Universitario Virgen de las Nieves, Granada, Spain.

出版信息

Tissue Antigens. 2001 Feb;57(2):138-43. doi: 10.1034/j.1399-0039.2001.057002138.x.

DOI:10.1034/j.1399-0039.2001.057002138.x
PMID:11260508
Abstract

We have studied the allele distribution of DRB1, DQB1 and DPB1 loci in 80 unrelated Gypsies living in different eastern areas of the Andalusian province of Granada (southern Spain). The frequency distribution of HLA class II alleles and the genetic distance of Andalusian Gypsies from several Caucasian populations indicate a marked similarity - but not total - of the former with the Gypsy population previously studied in Madrid (central Spain), which suggests that both groups migrated together out of India. In terms of genetic distance, both Gypsy groups are more like the Czech Gypsies and the Northern Indian groups than their neighbouring Caucasian non-Gypsy populations. In summary our data support the hypothesis of a common anthropological origin of all three European Gypsy groups, which probably split up after their arrival in Europe.

摘要

我们研究了居住在西班牙南部安达卢西亚省格拉纳达不同东部地区的80名无亲缘关系的吉普赛人的DRB1、DQB1和DPB1基因座的等位基因分布。HLA II类等位基因的频率分布以及安达卢西亚吉普赛人与几个高加索人群体的遗传距离表明,前者与之前在西班牙中部马德里研究过的吉普赛人群体有显著的相似性,但并非完全相同,这表明这两个群体是一起从印度迁移出来的。就遗传距离而言,这两个吉普赛群体与其相邻的高加索非吉普赛人群体相比,更类似于捷克吉普赛人和北印度群体。总之,我们的数据支持了所有三个欧洲吉普赛群体有共同人类学起源的假设,他们可能在抵达欧洲后才分开。

相似文献

1
HLA class II allele distribution in the Gypsy community of Andalusia, southern Spain.西班牙南部安达卢西亚吉普赛人群体中HLA II类等位基因分布情况。
Tissue Antigens. 2001 Feb;57(2):138-43. doi: 10.1034/j.1399-0039.2001.057002138.x.
2
HLA class I (A, B, C) and class II (DRB1, DQA1, DQB1, DPB1) alleles and haplotypes in the Han from southern China.中国南方汉族人群的HLA I类(A、B、C)和II类(DRB1、DQA1、DQB1、DPB1)等位基因及单倍型
Tissue Antigens. 2007 Dec;70(6):455-63. doi: 10.1111/j.1399-0039.2007.00932.x. Epub 2007 Sep 27.
3
Systemic lupus erythematosus in southern Spain: a comparative clinical and genetic study between Caucasian and Gypsy patients.西班牙南部的系统性红斑狼疮:白种人和吉普赛患者之间的临床与遗传学比较研究
Lupus. 2004;13(12):934-40. doi: 10.1191/0961203304lu2036oa.
4
Comparison of HLA class II alleles in Gypsy and Czech populations by DNA typing with oligonucleotide probes.采用寡核苷酸探针DNA分型法比较吉普赛人和捷克人群中HLAⅡ类等位基因
Tissue Antigens. 1992 Mar;39(3):111-6. doi: 10.1111/j.1399-0039.1992.tb01919.x.
5
Allele frequencies and haplotypic associations defined by allelic DNA typing at HLA class I and class II loci in the Japanese population.日本人群中通过HLA I类和II类基因座的等位基因DNA分型定义的等位基因频率和单倍型关联。
Tissue Antigens. 2000 Dec;56(6):522-9. doi: 10.1034/j.1399-0039.2000.560606.x.
6
HLA-DRB1, -DQB1 and -DPB1 polymorphism in the Slovak population.斯洛伐克人群中HLA - DRB1、- DQB1和 - DPB1基因多态性
Tissue Antigens. 1998 May;51(5):574-6. doi: 10.1111/j.1399-0039.1998.tb02996.x.
7
HLA class II polymorphism in the Ticuna of Brazil: evolutionary implications of the DRB1*0807 allele.巴西提库纳人的HLA II类基因多态性:DRB1*0807等位基因的进化意义
Tissue Antigens. 1998 Jan;51(1):41-50. doi: 10.1111/j.1399-0039.1998.tb02945.x.
8
Major histocompatibility complex class II alleles in an Uygur population in the Silk Route of Northwest China.中国西北丝绸之路维吾尔族人群中的主要组织相容性复合体II类等位基因
Tissue Antigens. 1998 Mar;51(3):287-92. doi: 10.1111/j.1399-0039.1998.tb03104.x.
9
Locus and population specific evolution in HLA class II genes.HLA II类基因中的基因座特异性和群体特异性进化
Ann Hum Genet. 1999 Jan;63(Pt 1):27-43. doi: 10.1046/j.1469-1809.1999.6310027.x.
10
Multiple sclerosis in Gypsies from southern Spain: prevalence, mitochondrial DNA haplogroups and HLA class II association.西班牙南部吉普赛人中的多发性硬化症:患病率、线粒体DNA单倍群及与HLA II类分子的关联
Tissue Antigens. 2008 May;71(5):426-33. doi: 10.1111/j.1399-0039.2008.01016.x. Epub 2008 Feb 28.

引用本文的文献

1
High-resolution characterization of allelic and haplotypic HLA frequency distribution in a Spanish population using high-throughput next-generation sequencing.采用高通量下一代测序技术对西班牙人群 HLA 等位基因和单倍型频率分布进行高分辨率分析。
Hum Immunol. 2019 Jul;80(7):429-436. doi: 10.1016/j.humimm.2019.02.005. Epub 2019 Feb 11.
2
Complement component C7 deficiency in two Spanish families.两个西班牙家庭中的补体成分C7缺乏症
Immunology. 2004 Dec;113(4):518-23. doi: 10.1111/j.1365-2567.2004.01997.x.