Keller R B, Baez-Giangreco A
Clin Orthop Relat Res. 1975 Jan-Feb(106):198-205.
Three cases of a distinctive soft tissue fibrous tumor with spotty calcification demonstrate the lesion originally described by Keasby as Juvenile Aponeurotic Fibroma. The tumor tends to occur on the volar surface of the hands and feet in children and adolescents but may be seen in other areas in all age groups. Size rarely exceeds 3.0 cm. The tumors are fixed to the fascial layers. In previously reported patients pain was not described as an important factor, but both pain and tenderness were striking in all 3 of our cases. Microscopically the dominant feature is a fribrous stromal pattern of fusiform cells with inclusions of mast cells. Spotty calcification is a constant finding and appears to increase with duration of tumor. Local recurrence after excision and an aggressive histologic appearance may raise the question of malignancy. However, neither destruction of normal tissue surrounding the tumor nor metastases have occurred. Local exicision is the treatment of choice.
三例具有斑点状钙化的独特软组织纤维瘤病例，显示了最初由基斯比描述为青少年腱膜纤维瘤的病变。该肿瘤倾向于发生在儿童和青少年的手足掌面，但在所有年龄组的其他部位也可见到。大小很少超过3.0厘米。肿瘤与筋膜层固定。在先前报道的患者中，疼痛并非重要因素，但在我们的所有3例病例中，疼痛和压痛都很明显。显微镜下，主要特征是梭形细胞的纤维性基质模式，伴有肥大细胞包涵体。斑点状钙化是一个恒定的发现，并且似乎随着肿瘤持续时间的增加而增加。切除后局部复发以及侵袭性的组织学表现可能会引发恶性肿瘤的问题。然而，肿瘤周围的正常组织既未被破坏也未发生转移。局部切除是首选的治疗方法。
