Carter F A, Bulik C M, McIntosh V V, Joyce P R
Department of Psychological Medicine, Christchurch School of Medicine, University of Otago, P.O. Box 4345, Christchurch, New Zealand.
Int J Eat Disord. 2001 Apr;29(3):336-44. doi: 10.1002/eat.1027.
To examine changes in cue reactivity following cognitive-behavior therapy (CBT) for bulimia nervosa and to evaluate whether changes are associated with treatment modality or treatment outcome.
Subjects were 135 women (17-45 years old) with a current, primary diagnosis of bulimia nervosa. They were participants in a randomized clinical trial examining the additive efficacy of exposure and nonexposure-based behavior therapy to a core of CBT. Physiological, self-report, and behavioral measures of cue reactivity to individualized high-risk binge foods were obtained at pretreatment and posttreatment. Primary, secondary, and tertiary outcome measures are reported for posttreatment.
Bulimic patients experienced significant changes in cue reactivity following treatment. With the exception of salivary reactivity, patients experienced less reactivity at posttreatment. Changes in cue reactivity were not related to treatment modality, but were related to positive treatment outcome for self-report measures of cue reactivity.
Favorable treatment outcome among bulimic women is associated with low cue reactivity on self-report measures at posttreatment.
研究神经性贪食症患者接受认知行为疗法（CBT）后线索反应性的变化，并评估这些变化是否与治疗方式或治疗结果相关。
研究对象为135名年龄在17至45岁之间、目前主要诊断为神经性贪食症的女性。她们参与了一项随机临床试验，该试验旨在研究基于暴露和非暴露的行为疗法对CBT核心疗法的增效作用。在治疗前和治疗后，获取了对个体化高风险暴食食物的线索反应性的生理、自我报告和行为测量数据。报告了治疗后的主要、次要和三级结局指标。
贪食症患者在治疗后线索反应性发生了显著变化。除唾液反应性外，患者在治疗后的反应性降低。线索反应性的变化与治疗方式无关，但与线索反应性自我报告测量的积极治疗结果相关。
贪食症女性患者良好的治疗结果与治疗后自我报告测量的低线索反应性相关。
