Herszkowicz N, Barbato A, Salvi W, Pinheiro D, Pantaleão D, Halpern A, Cerri G G
InRad, Institute of Radiology, and Group of Obisity and Metabolic Diseases of the Endocrinology Service, Hospital das Clínicas, University of São Paulo, Brazil.
Arq Bras Cardiol. 2001 Mar;76(3):189-96. doi: 10.1590/s0066-782x2001000300002.
To study by doppler echocardiography the cardiac systolic and diastolic functions of health, uncomplicated obese subjects.
Fifty-nine obese women with an average body mass index (BMI) of 35 kg/m2 were evaluated and compared with 19 subjects with an average BMI of 23 kg/m2 (control group).
In the obese group, a clear tendency was observed toward higher systolic pressure, increased wall thickness and, consequently, myocardial mass, elevation on the circumference stress of the left ventricular wall, and an indisputable presence of diastolic abnormalities. Filling abnormalities were observed with impaired relaxation, with prolonged isovolumic relaxation time (IVRT) and augmented atrium contribution representing early indexes of cardiac dysfunction when systolic performance is still normal.
Obesity is generally a chronic condition, and doppler echocardiography can be used as a noninvasive instrument for early evaluation of left ventricular diastolic indexes.
通过多普勒超声心动图研究健康、无并发症肥胖受试者的心脏收缩和舒张功能。
对59名平均体重指数（BMI）为35kg/m²的肥胖女性进行评估，并与19名平均BMI为23kg/m²的受试者（对照组）进行比较。
在肥胖组中，观察到明显的趋势，即收缩压升高、壁厚度增加，进而心肌质量增加、左心室壁圆周应力升高，以及无可争议的舒张功能异常。观察到充盈异常，伴有舒张功能受损、等容舒张时间（IVRT）延长和心房贡献增加，这些是心脏功能障碍早期指标，此时收缩功能仍正常。
肥胖通常是一种慢性疾病，多普勒超声心动图可作为早期评估左心室舒张指标的无创工具。
