Dios E, Saornil M A, Herreras J M
Instituto de Oftalmobiología Aplicada (IOBA), Department of Ophthalmology, Hospital Universitario de Valladolid, Spain.
Ocul Immunol Inflamm. 2001 Mar;9(1):59-64. doi: 10.1076/ocii.9.1.59.3982.
Sarcoidosis is a multisystem granulomatous disease of unknown etiology that can affect almost every organ in the body, particularly the lungs, skin, eyes, and thoracic lymph nodes. A definitive diagnosis of sarcoidosis requires that a biopsy be performed. A specimen can be obtained from any affected ocular structure, including conjunctiva, lacrimal gland, eyelid skin, and orbit. Among them, conjunctival biopsy has been suggested as a sensible and safe procedure for confirming suspected sarcoidosis. We describe three patients in whom ocular symptoms were the sole initial manifestations of sarcoidosis and who were diagnosed based on the results of a conjunctival biopsy. We also discuss the efficacy of and indications for conjunctival biopsy.
结节病是一种病因不明的多系统肉芽肿性疾病，可累及身体几乎每个器官，尤其是肺、皮肤、眼睛和胸内淋巴结。结节病的明确诊断需要进行活检。可从任何受影响的眼部结构获取标本，包括结膜、泪腺、眼睑皮肤和眼眶。其中，结膜活检被认为是确诊疑似结节病的一种合理且安全的方法。我们描述了三名患者，他们的眼部症状是结节病最初的唯一表现，并根据结膜活检结果确诊。我们还讨论了结膜活检的疗效和适应证。
