Gundlach E, Temmesfeld-Wollbrück B, Pleyer U
Augenklinik, Campus Virchow-Klinikum, Charité, Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Deutschland.
Med. Klinik m. S. Infektiologie und Pneumologie, Campus Mitte, Charité, Universitätsmedizin Berlin, Berlin, Deutschland.
Ophthalmologe. 2017 Sep;114(9):865-876. doi: 10.1007/s00347-017-0552-5.
Sarcoidosis is a multisystem disorder of unknown cause. Ophthalmic involvement occurs in up to 60% of all patients, often as the first manifestation of sarcoidosis. Because of the heterogeneous clinical presentation diagnosis can be difficult; therefore the International Workshop on Ocular Sarcoidosis (IWOS 2009) diagnostic criteria based on clinical presentation, laboratory investigations and imaging techniques enable establishment of the diagnosis. Patients suffering from sarcoidosis should be treated by both ophthalmologists and internal physicians. Corticosteroids are commonly used for treatment, although in some patients the therapy has to be escalated by further immunosuppressants. Finally, a good cooperation between ophthalmologists and internal physicians results in a mostly good prognosis.
结节病是一种病因不明的多系统疾病。高达60%的患者会出现眼部受累，且常常是结节病的首发表现。由于临床表现具有异质性，诊断可能会很困难；因此，2009年国际眼部结节病研讨会（IWOS 2009）基于临床表现、实验室检查和成像技术制定的诊断标准有助于确诊。结节病患者应由眼科医生和内科医生共同治疗。皮质类固醇常用于治疗，不过在一些患者中，治疗必须通过进一步使用免疫抑制剂来加强。最后，眼科医生和内科医生之间的良好合作通常会带来较好的预后。
