Iodine monochloride/silver trifluoromethanesulfonate (ICI/AgOTf) as a convenient promoter system for O-glycoside synthesis.
作者信息
Ercegovic T, Meijer A, Magnusson G, Ellervik U
机构信息
Organic Chemistry, Center for Chemistry and Chemical Engineering, University of Lund, P.O. Box 124, SE-221 00 Lund, Sweden.
出版信息
Org Lett. 2001 Mar 22;3(6):913-5. doi: 10.1021/ol015547c.
PMID:11263914
Abstract
The novel promoter system iodine monochloride/silver trifluoromethanesulfonate (ICl/AgOTf) was evaluated with various thioglycoside donors and saccharide acceptors, and O-glycosides were obtained in 46-82% yield. Several practical advantages of the ICl/AgOTf system over known promoter systems were observed, such as convenient handling of the reagents and absence of byproducts related to N-succinimide.
摘要
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