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使用双探测器螺旋CT血管造影术检测疑似肺栓塞患者的深静脉血栓形成:诊断价值及其他发现。

Using dual-detector helical CT angiography to detect deep venous thrombosis in patients with suspicion of pulmonary embolism: diagnostic value and additional findings.

作者信息

Coche E E, Hamoir X L, Hammer F D, Hainaut P, Goffette P P

机构信息

Department of Radiology, Cliniques Universitaires St-Luc, av. Hippocrate 10, B-1200 Brussels, Belgium.

出版信息

AJR Am J Roentgenol. 2001 Apr;176(4):1035-9. doi: 10.2214/ajr.176.4.1761035.

DOI:10.2214/ajr.176.4.1761035
PMID:11264105
Abstract

OBJECTIVE

The purpose of this study was to assess the value of dual-slice helical CT angiography in detecting deep venous thrombosis in patients in whom acute pulmonary embolism was suspected and to describe the additional extrathoracic findings.

SUBJECTS AND METHODS

Sixty-five consecutive patients were examined for suspected pulmonary embolism using helical CT of the chest (2.7-mm collimation; table speed, 7.5 mm/sec; 100-140 mL of contrast medium injected at a rate of 3 mL/sec) followed by CT of the lower limbs (6.5-mm collimation; table speed, 10 mm/sec) without any additional contrast medium injection. Sequential scanning of the abdomen was performed using 10-mm collimation and an interval of 40 mm. Color Doppler sonography of the lower limbs was done within 24 hr of CT by two radiologists who were unaware of CT findings. Results of CT venography were compared with those of Doppler sonography and with phlebography or repeated focalized sonography in cases of discrepancy.

RESULTS

Twenty-two patients had pulmonary embolism revealed on chest CT. Sixteen patients had a deep venous thrombosis. Thirteen patients with pulmonary embolism had a deep venous thrombosis. Three patients with deep venous thrombosis had no pulmonary embolism. Sensitivity and specificity for diagnosing deep venous thrombosis with CT was 93% and 97%, respectively (kappa = 0.88). Additional extrathoracic findings were observed in four patients.

CONCLUSION

Combined CT venography with dual-slice scanning is an accurate method to diagnose deep venous thrombosis that may reveal additional imaging findings in some patients with possible pulmonary embolism.

摘要

目的

本研究旨在评估双层螺旋CT血管造影术在检测疑似急性肺栓塞患者深静脉血栓形成中的价值,并描述额外的胸外发现。

对象与方法

连续65例疑似肺栓塞患者接受胸部螺旋CT检查(准直2.7mm;床速7.5mm/秒;以3ml/秒的速率注射100 - 140ml造影剂),随后进行下肢CT检查(准直6.5mm;床速10mm/秒),无需额外注射造影剂。腹部采用10mm准直和40mm间隔进行连续扫描。在CT检查后24小时内,由两名不知CT检查结果的放射科医生对下肢进行彩色多普勒超声检查。将CT静脉造影结果与多普勒超声检查结果以及在结果存在差异的情况下与静脉造影或重复局部超声检查结果进行比较。

结果

22例患者胸部CT显示有肺栓塞。16例患者存在深静脉血栓形成。13例肺栓塞患者有深静脉血栓形成。3例深静脉血栓形成患者无肺栓塞。CT诊断深静脉血栓形成的敏感性和特异性分别为93%和97%(kappa = 0.88)。4例患者观察到额外的胸外发现。

结论

双层螺旋CT联合静脉造影是诊断深静脉血栓形成的准确方法,在一些可能患有肺栓塞的患者中可能会显示出额外的影像学发现。

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