Li J, Li S, Feuers R J, Buffington C K, Cowan G S
Guangzhou Institute of Respiratory Disease, Guangzhou, People's Republic of China.
Respirology. 2001 Mar;6(1):9-13. doi: 10.1046/j.1440-1843.2001.00290.x.
The aim of this study was to determine the effects of fat distribution on aerobic and ventilatory response to exercise testing in morbidly obese (MO) females.
The study population consisted of 164 MO females, 55% (n = 90) with upper body or abdominal adiposity (UBD), as defined by waist-hip circumference ratio (WHR) > or = 0.80, and 45% (n = 74) with lower body fat distribution (LBD) (WHR < 0.80). An incremental exercise testing on cycle ergometer was performed to determine the effect of exercise on oxygen consumption (VO2), carbon dioxide production (VCO2), minute ventilation (VE), tidal volume (VT), respiratory rate (fb) and heart rate (HR).
Upper body adiposity individuals had significantly higher VO2 and VCO2 than LBD subjects (P < 0.05) from 0 watt (W) of pedalling up to their anaerobic threshold (AT) and maximal exercise. VE was significantly higher in UBD subjects compared with LBD subjects, from 20 W during exercise up to AT and peak work levels (P < 0.05). Upper body adiposity group also had a significantly higher fb than the LBD group at rest, after each workload and at AT and peak exercise work rates (P < 0.05). VT was lower in UBD subjects at free pedalling and up to AT and peak workload with significant difference at 60 and 80 W (P < 0.05). The anaerobic threshold, expressed as work rate, was significantly lower in the UBD subjects (P < 0.05) and peak workload achieved did not differ significantly between the two groups.
Upper body adiposity subjects had higher oxygen requirement, more rapid and shallow breathing, higher ventilatory demand, but lower anaerobic threshold than the LBD individuals during progressive exercise. It suggests that the cardiopulmonary endurance to exercise in MO patients with upper body fat distribution is lower than in those with lower body fat distribution.
本研究旨在确定脂肪分布对病态肥胖（MO）女性运动测试中需氧量和通气反应的影响。
研究对象为164名MO女性，其中55%（n = 90）为上身或腹部肥胖（UBD），根据腰臀围比（WHR）≥0.80定义；45%（n = 74）为下身脂肪分布（LBD）（WHR < 0.80）。通过在自行车测力计上进行递增运动测试，以确定运动对耗氧量（VO2）、二氧化碳生成量（VCO2）、分钟通气量（VE）、潮气量（VT）、呼吸频率（fb）和心率（HR）的影响。
从蹬踏0瓦（W）直至无氧阈（AT）和最大运动量，上身肥胖个体的VO2和VCO2显著高于LBD受试者（P < 0.05）。从运动时20 W直至AT和峰值工作水平，UBD受试者的VE显著高于LBD受试者（P < 0.05）。上身肥胖组在静息状态、每个工作量后、AT和峰值运动工作率时的fb也显著高于LBD组（P < 0.05）。在自由蹬踏时以及直至AT和峰值工作量，UBD受试者的VT较低，在60和80 W时存在显著差异（P < 0.05）。以工作率表示的无氧阈在UBD受试者中显著较低（P < 0.05），两组达到的峰值工作量无显著差异。
在进行递增运动时，上身肥胖受试者比LBD个体有更高的需氧量、更快且更浅的呼吸、更高的通气需求，但无氧阈更低。这表明上身脂肪分布的MO患者对运动的心肺耐力低于下身脂肪分布的患者。
