Roubaud V, Rizzi C, Guérin S, Lauricella R, Bouteiller J C, Tuccio B
Laboratoire SREP, UMR 6517 CNRS-Universités d'Aix -Marseille 1 et 3, Case 541, 13397 Marseille Cedex 20, France.
Free Radic Res. 2001 Mar;34(3):237-49. doi: 10.1080/10715760100300221.
2-(Diethylphosphonate)-nitrosopropane (DEPNP), prepared by oxidation of the corresponding aminophosphonate, was found to essentially exist as monomer in both water and organic solvents. The mechanisms of its degradation under 80 degrees C heating or visible light exposure were studied by EPR spectroscopy: its decomposition gave rise to paramagnetic by-products, which have been identified as DEPNP/.C(CH(3) )(2) [P(O)(OC(2) H(5) )(2) ] and DEPNP/.P(O)(OC(2) H(5) )(2) spin adducts. Despite this drawback, DEPNP was successfully used as spin trapping agents to scavenge various carbon - and phosphorus-centred free radicals both in aqueous and organic media, giving rise to intense EPR spectra characteristic of the species trapped.
通过相应氨基膦酸的氧化制备的2-(二乙基亚磷酸酯)-亚硝基丙烷(DEPNP)，发现在水和有机溶剂中基本以单体形式存在。通过电子顺磁共振光谱研究了其在80℃加热或可见光照射下的降解机制：其分解产生了顺磁性副产物，已鉴定为DEPNP/.C(CH(3))(2)[P(O)(OC(2)H(5))(2)]和DEPNP/.P(O)(OC(2)H(5))(2)自旋加合物。尽管有这个缺点，DEPNP仍成功用作自旋捕获剂，在水性和有机介质中清除各种以碳和磷为中心的自由基，产生所捕获物种特有的强烈电子顺磁共振光谱。
