Carr A B, Larsen P E, Gerard D A
Mayo Graduate School of Medicine, Rochester, Minn 55905, USA.
J Prosthet Dent. 2001 Mar;85(3):276-80. doi: 10.1067/mpr.2001.114821.
A complete understanding of dental implant prognosis requires better knowledge of the bone anatomy after implant healing. Such baseline data are necessary to compare against load-induced changes in anatomy.
The purpose of this article is to describe and compare measures of implant support (percentage [%] integration and percentage [%] bone area) for various implants in baboon jaws after healing times of 3 and 6 months.
Commercially pure titanium (cpTi) and titanium alloy (Ti-alloy) screw-shaped implants were placed in the posterior jaws of 9 female baboons after 2 months of postextraction healing. Specimens were harvested after 3 months (5 baboons: 8 cpTi, 7 Ti-alloy) and after 6 months (4 baboons: 8 cpTi, 8 Ti-alloy). Each implant provided 6 polished horizontal sections for data collection, which was accomplished from digitized images with the IMAGE analysis system (reliability at 1.6%). Three- and six-month data for each parameter were compared with the use of ANOVA (P<.01).
The results revealed a significant increase in the % integration (cpTi 39.1 to 56.2; Ti-alloy 40.0 to 55.2) and the % bone area (cpTi 38.8 to 47.9; Ti-alloy 38.9 to 49.2) from 3 to 6 months for both implants. This significant increase was also true for comparisons by jaw for each implant material (P<.01 for overall and by jaw comparisons).
A time-dependent increase in jawbone anchorage was measured in this nonhuman primate population, and it was shown that the 6-month maxillary data were comparable to the 3-month mandibular data. These results lend support to the clinical strategy of waiting longer to load implants in the maxilla.
要全面了解牙种植体的预后情况，需要更深入地了解种植体愈合后的骨解剖结构。此类基线数据对于与负荷引起的解剖结构变化进行比较是必要的。
本文旨在描述和比较在愈合3个月和6个月后，狒狒颌骨中各种种植体的种植体支持测量指标（整合百分比[%]和骨面积百分比[%]）。
在拔牙后愈合2个月后，将商业纯钛（cpTi）和钛合金（Ti合金）螺旋形种植体植入9只雌性狒狒的后颌骨。在3个月后（5只狒狒：8个cpTi，7个Ti合金）和6个月后（4只狒狒：8个cpTi，8个Ti合金）采集标本。每个种植体提供6个用于数据收集的抛光水平切片，通过IMAGE分析系统从数字化图像中完成数据收集（可靠性为1.6%）。使用方差分析（P<0.01）比较每个参数的3个月和6个月数据。
结果显示，两种种植体从3个月到6个月，整合百分比（cpTi从39.1到56.2；Ti合金从40.0到55.2）和骨面积百分比（cpTi从38.8到47.9；Ti合金从38.9到49.2）均显著增加。对于每种种植体材料按颌骨进行比较时，这种显著增加也成立（总体和按颌骨比较均为P<0.01）。
在这个非人灵长类动物群体中测量到颌骨锚固随时间增加，并且表明6个月的上颌数据与3个月的下颌数据相当。这些结果支持了上颌种植体延迟加载的临床策略。
