[The mechanism of action of parenterally administered protein hydrolysates on the exocrine activity of the pancreas].

In dogs with fistulae of the stomach and the pancreatic duct as well as in dogs with artificially made partition between the stomach and the duodenum, effect of protein hydrolysates administered into the blood, on the pancreas secretion, was shown to manifest itself only in conditions of unopposed transition of the stomach acid contents into the duodenum. In the mechanism of protein hydrolysates action on the pancreas secretion, the major part is played by their ability to stimulate the stomach secretion and the transition of the acid content into the duodenum. Under the influence of the acid contents, release of the secretin occurs in the duodenum which induces the secretion of the pancreatic juice.